node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EEN82501.1 | adk | POREN0001_1814 | POREN0001_1248 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.434 |
EEN82501.1 | guaA | POREN0001_1814 | POREN0001_0320 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.802 |
EEN82501.1 | hpt | POREN0001_1814 | POREN0001_1247 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | 0.810 |
EEN82501.1 | rdgB | POREN0001_1814 | POREN0001_1196 | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.803 |
EEN83253.1 | EEN83449.1 | POREN0001_1121 | POREN0001_0577 | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.536 |
EEN83253.1 | adk | POREN0001_1121 | POREN0001_1248 | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.805 |
EEN83253.1 | cgtA | POREN0001_1121 | POREN0001_1249 | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.400 |
EEN83253.1 | gmk | POREN0001_1121 | POREN0001_0022 | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.665 |
EEN83253.1 | guaA | POREN0001_1121 | POREN0001_0320 | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.999 |
EEN83253.1 | hpt | POREN0001_1121 | POREN0001_1247 | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | 0.921 |
EEN83253.1 | purA | POREN0001_1121 | POREN0001_1329 | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.977 |
EEN83253.1 | purH | POREN0001_1121 | POREN0001_0373 | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | Putative phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142. | 0.974 |
EEN83253.1 | rdgB | POREN0001_1121 | POREN0001_1196 | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.923 |
EEN83449.1 | EEN83253.1 | POREN0001_0577 | POREN0001_1121 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | 0.536 |
EEN83449.1 | adk | POREN0001_0577 | POREN0001_1248 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.443 |
EEN83449.1 | guaA | POREN0001_0577 | POREN0001_0320 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | GMP synthase (glutamine-hydrolyzing) domain protein; Catalyzes the synthesis of GMP from XMP. | 0.611 |
EEN83449.1 | hpt | POREN0001_0577 | POREN0001_1247 | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | Putative hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156. | 0.948 |
adk | EEN82501.1 | POREN0001_1248 | POREN0001_1814 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Identified by match to protein family HMM PF03819; match to protein family HMM TIGR00444. | 0.434 |
adk | EEN83253.1 | POREN0001_1248 | POREN0001_1121 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Inosine 5-monophosphate dehydrogenase; Identified by match to protein family HMM PF00478; match to protein family HMM PF00571. | 0.805 |
adk | EEN83449.1 | POREN0001_1248 | POREN0001_0577 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | Purine nucleoside phosphorylase I, inosine and guanosine-specific; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.443 |