STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEN83356.18-amino-7-oxononanoate synthase; This gene contains a nucleotide ambiguity which may be the result of a sequencing error; identified by match to protein family HMM PF00155. (414 aa)    
Predicted Functional Partners:
EEN83358.1
Identified by match to protein family HMM PF04301.
 
 
  0.980
bioA
Adenosylmethionine-8-amino-7-oxononanoate transaminase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.
 
 
 0.955
bioC
Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway.
 
 
  0.901
bioF
Putative 8-amino-7-oxononanoate synthase; Identified by match to protein family HMM PF00155; match to protein family HMM PF00202; match to protein family HMM PF00266.
  
  
 
0.847
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
 
 
 0.809
bioB
Putative biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
 
 0.673
gcvP
Glycine dehydrogenase; Identified by match to protein family HMM PF02347; match to protein family HMM TIGR00461; Belongs to the GcvP family.
  
 
 0.667
EEN83355.1
Antioxidant, AhpC/TSA family; Identified by match to protein family HMM PF00085; match to protein family HMM PF00578; match to protein family HMM PF08534.
       0.655
EEN83274.1
Aminotransferase, class I/II; Identified by match to protein family HMM PF00155.
  
  
 
0.546
kbl
Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
  
 
0.508
Your Current Organism:
Porphyromonas endodontalis
NCBI taxonomy Id: 553175
Other names: P. endodontalis ATCC 35406, Porphyromonas endodontalis ATCC 35406, Porphyromonas endodontalis str. ATCC 35406, Porphyromonas endodontalis strain ATCC 35406
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.