STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEB64508.1C-5 cytosine-specific DNA methylase; Identified by match to protein family HMM PF00145. (243 aa)    
Predicted Functional Partners:
metK
Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
    
 0.921
mtnN
MTA/SAH nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
    
  0.902
EEB64503.1
Identified by match to protein family HMM PF03235.
  
  
 0.813
EEB64504.1
Hypothetical protein.
       0.786
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
     0.774
EEB65713.1
Transketolase, pyridine binding domain protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
  
     0.774
EEB64933.1
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR01349.
  
     0.686
EEB66445.1
Transketolase, C-terminal domain protein; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM PF02780.
  
     0.585
pdhC_2
2-oxo acid dehydrogenase acyltransferase (catalytic domain); Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
  
     0.501
EEB64509.1
Hypothetical protein; Identified by glimmer; putative.
       0.470
Your Current Organism:
Capnocytophaga sputigena
NCBI taxonomy Id: 553177
Other names: C. sputigena ATCC 33612, Capnocytophaga sputigena ATCC 33612, Capnocytophaga sputigena Capno, Capnocytophaga sputigena str. ATCC 33612, Capnocytophaga sputigena strain ATCC 33612
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.