STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (542 aa)    
Predicted Functional Partners:
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.999
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.999
trpF
N-(5'phosphoribosyl)anthranilate isomerase; Identified by match to protein family HMM PF00697; Belongs to the TrpF family.
 
 0.999
trpC
Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family.
  
 0.999
EEB65255.1
Chorismate binding enzyme; Identified by match to protein family HMM PF00425.
 0.999
EEB64572.1
Para-aminobenzoate synthase component I; Identified by match to protein family HMM PF00425.
 0.999
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.987
EEB66880.1
Putative 3-deoxy-7-phosphoheptulonate synthase; Identified by match to protein family HMM PF00793; match to protein family HMM PF01817.
  
 
 0.980
EEB66192.1
Isochorismate synthase; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.
 
 
 0.950
EEB65387.1
Putative homoserine O-acetyltransferase; Identified by match to protein family HMM PF00561; Belongs to the AB hydrolase superfamily. MetX family.
  
  
 0.882
Your Current Organism:
Capnocytophaga sputigena
NCBI taxonomy Id: 553177
Other names: C. sputigena ATCC 33612, Capnocytophaga sputigena ATCC 33612, Capnocytophaga sputigena Capno, Capnocytophaga sputigena str. ATCC 33612, Capnocytophaga sputigena strain ATCC 33612
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