STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucAOxoglutarate dehydrogenase (succinyl-transferring), E1 component; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239. (924 aa)    
Predicted Functional Partners:
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.999
pdhC_2
2-oxo acid dehydrogenase acyltransferase (catalytic domain); Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 0.998
lpdA-2
Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
 
 0.990
lpdA
Dihydrolipoyl dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF00890; match to protein family HMM PF01134; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
  
 0.987
EEB64933.1
Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817; match to protein family HMM TIGR01349.
 0.951
sucC
succinate-CoA ligase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 
 0.917
EEB66323.1
Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF03971; match to protein family HMM TIGR00178; Belongs to the monomeric-type IDH family.
   
 
 0.915
EEB65364.1
Clostripain family; Identified by match to protein family HMM PF03415.
    
 
 0.910
sdhA
Succinate dehydrogenase flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF02910; match to protein family HMM TIGR01811.
 
 
 0.894
sucD
succinate-CoA ligase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.886
Your Current Organism:
Capnocytophaga sputigena
NCBI taxonomy Id: 553177
Other names: C. sputigena ATCC 33612, Capnocytophaga sputigena ATCC 33612, Capnocytophaga sputigena Capno, Capnocytophaga sputigena str. ATCC 33612, Capnocytophaga sputigena strain ATCC 33612
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.