STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEB66504.1Hydrolase, alpha/beta domain protein; Identified by match to protein family HMM PF07859. (328 aa)    
Predicted Functional Partners:
EEB66467.1
Hypothetical protein; Identified by glimmer; putative.
       0.762
EEB66561.1
Hypothetical protein.
       0.721
fdx
4Fe-4S binding domain protein; Identified by match to protein family HMM PF00037.
   
   0.560
petC1
Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355.
    
   0.515
cutC
CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family.
  
    0.495
fadK
AMP-binding domain protein; Identified by match to protein family HMM PF00501.
 
 
 0.487
gyrA
DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
       0.486
EEB66494.1
Peptidase M16 inactive domain protein; Identified by match to protein family HMM PF00675; match to protein family HMM PF05193; Belongs to the peptidase M16 family.
    
 
 0.478
EEB65754.1
Hypothetical protein.
   
   0.437
EEB65706.1
NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368; match to protein family HMM PF07993; match to protein family HMM PF09346.
   
   0.437
Your Current Organism:
Capnocytophaga sputigena
NCBI taxonomy Id: 553177
Other names: C. sputigena ATCC 33612, Capnocytophaga sputigena ATCC 33612, Capnocytophaga sputigena Capno, Capnocytophaga sputigena str. ATCC 33612, Capnocytophaga sputigena strain ATCC 33612
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.