STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEB64615.1ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; Identified by match to protein family HMM PF00183; match to protein family HMM PF02518. (631 aa)    
Predicted Functional Partners:
EEB65509.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; Identified by match to protein family HMM PF00160; match to protein family HMM PF00254.
  
 0.996
EEB66559.1
Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; Identified by match to protein family HMM PF00160; match to protein family HMM PF00254.
  
 0.996
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.995
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.897
EEB65736.1
DnaJ domain protein; Identified by match to protein family HMM PF00226.
  
 0.872
EEB65092.1
Identified by match to protein family HMM PF00226; match to protein family HMM PF01556.
  
 0.867
EEB64903.1
DnaJ domain protein; Identified by match to protein family HMM PF00226.
  
 0.867
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 0.867
EEB64971.1
Hypothetical protein; Identified by glimmer; putative.
    
 0.826
EEB65508.1
Hypothetical protein.
    
 0.826
Your Current Organism:
Capnocytophaga sputigena
NCBI taxonomy Id: 553177
Other names: C. sputigena ATCC 33612, Capnocytophaga sputigena ATCC 33612, Capnocytophaga sputigena Capno, Capnocytophaga sputigena str. ATCC 33612, Capnocytophaga sputigena strain ATCC 33612
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.