STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EEK14900.16-O-methylguanine DNA methyltransferase, DNA binding domain protein; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (179 aa)    
Predicted Functional Partners:
EEK14610.1
Sigma-70, region 4; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
   
 
 0.853
EEK14889.1
Hypothetical protein; Identified by glimmer; putative.
       0.773
EEK14897.1
Hypothetical protein.
       0.720
EEK14881.1
Hypothetical protein; Identified by glimmer; putative.
       0.709
polA
DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.709
EEK14909.1
Hypothetical protein; Identified by glimmer; putative.
       0.703
lpxB
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
      0.660
EEK13933.1
Hypothetical protein.
      0.604
EEK14300.1
Identified by match to protein family HMM PF00582.
  
  
 0.600
EEK14360.1
Exonuclease, DNA polymerase III, epsilon subunit family; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573.
  
  
 0.597
Your Current Organism:
Capnocytophaga gingivalis
NCBI taxonomy Id: 553178
Other names: C. gingivalis ATCC 33624, Capnocytophaga gingivalis ATCC 33624, Capnocytophaga gingivalis JCVIHMP016, Capnocytophaga gingivalis str. ATCC 33624, Capnocytophaga gingivalis strain ATCC 33624
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