STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the thioester dehydratase family. FabZ subfamily. (465 aa)    
Predicted Functional Partners:
lpxA
acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
 
 0.998
lpxD-2
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
 
 0.995
lpxD
UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Identified by match to protein family HMM PF00132; match to protein family HMM PF04613.
 
 
 0.986
fabG
3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
 0.967
EEK14661.1
Hypothetical protein.
  
 
 0.958
EEK13642.1
Oxidoreductase, short chain dehydrogenase/reductase family protein; Identified by match to protein family HMM PF00106; match to protein family HMM PF08659.
  
 0.957
EEK15825.1
Putative enoyl-[acyl-carrier-protein] reductase II; Identified by match to protein family HMM PF03060.
  
 
 0.936
EEK15349.1
Hypothetical protein.
    
 0.915
fabD
[acyl-carrier-protein] S-malonyltransferase; Identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128.
 
  
 0.898
accD
acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
 
  
 0.868
Your Current Organism:
Capnocytophaga gingivalis
NCBI taxonomy Id: 553178
Other names: C. gingivalis ATCC 33624, Capnocytophaga gingivalis ATCC 33624, Capnocytophaga gingivalis JCVIHMP016, Capnocytophaga gingivalis str. ATCC 33624, Capnocytophaga gingivalis strain ATCC 33624
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