STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFL61850.1Hypothetical protein. (409 aa)    
Predicted Functional Partners:
SFL61831.1
3-isopropylmalate dehydrogenase.
 
     0.593
SFL61804.1
3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit.
       0.532
SFL61873.1
Phosphocarrier protein.
       0.488
SFL61689.1
Acetolactate synthase, large subunit.
       0.425
SFL61713.1
Acetolactate synthase, small subunit.
       0.425
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.425
SFL61763.1
Hypothetical protein.
       0.425
leuC-2
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
       0.425
SFL22932.1
Glucoamylase (glucan-1,4-alpha-glucosidase), GH15 family.
  
    0.416
Your Current Organism:
Halogranum rubrum
NCBI taxonomy Id: 553466
Other names: CGMCC 1.7738, H. rubrum, Halobacteriaceae archaeon RO2-11, Halogranum rubrum Cui et al. 2010, JCM 15772, strain RO2-11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.