STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
amzAArchaemetzincin; Probable zinc metalloprotease whose natural substrate is unknown. (173 aa)    
Predicted Functional Partners:
rtcA
RNA 3'-terminal phosphate cyclase (ATP); Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing.
 
     0.729
SFF85188.1
Hypothetical protein; Belongs to the UPF0146 family.
       0.634
SFF85214.1
Haloacid dehalogenase superfamily, subfamily IA hydrolase, TIGR01548.
       0.584
SFF85118.1
Nucleotide-binding universal stress protein, UspA family.
       0.570
SFF85308.1
Hypothetical protein.
 
     0.489
SFF98916.1
Hypothetical protein.
  
     0.468
SFF85256.1
Hypothetical protein.
       0.445
SFF85283.1
Hypothetical protein.
       0.445
fau-1
Ribonuclease G or E; Probable RNase involved in rRNA stability through maturation and/or degradation of precursor rRNAs. Binds to RNA in loop regions with AU-rich sequences.
  
     0.414
SFF90285.1
Hypothetical protein.
  
     0.400
Your Current Organism:
Halopelagius inordinatus
NCBI taxonomy Id: 553467
Other names: CGMCC 1.7739, H. inordinatus, Halobacteriaceae archaeon RO5-14, Halobacteriaceae archaeon RO5-2, Halopelagius inordinatus Cui et al. 2010, JCM 15773, strain RO5-2
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