node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFF75308.1 | SFF95874.1 | SAMN04488063_0137 | SAMN04488063_0927 | Cell division control protein 6; Involved in regulation of DNA replication. | DNA polymerase I. | 0.823 |
SFF75308.1 | atpF | SAMN04488063_0137 | SAMN04488063_0415 | Cell division control protein 6; Involved in regulation of DNA replication. | V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.473 |
SFF75308.1 | pcn | SAMN04488063_0137 | SAMN04488063_0304 | Cell division control protein 6; Involved in regulation of DNA replication. | Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.737 |
SFF75308.1 | priL | SAMN04488063_0137 | SAMN04488063_0301 | Cell division control protein 6; Involved in regulation of DNA replication. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.815 |
SFF75308.1 | rfcL | SAMN04488063_0137 | SAMN04488063_2064 | Cell division control protein 6; Involved in regulation of DNA replication. | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.596 |
SFF75308.1 | top6A | SAMN04488063_0137 | SAMN04488063_2898 | Cell division control protein 6; Involved in regulation of DNA replication. | DNA topoisomerase-6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.401 |
SFF75308.1 | top6B | SAMN04488063_0137 | SAMN04488063_2899 | Cell division control protein 6; Involved in regulation of DNA replication. | DNA topoisomerase-6 subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.633 |
SFF95874.1 | SFF75308.1 | SAMN04488063_0927 | SAMN04488063_0137 | DNA polymerase I. | Cell division control protein 6; Involved in regulation of DNA replication. | 0.823 |
SFF95874.1 | atpF | SAMN04488063_0927 | SAMN04488063_0415 | DNA polymerase I. | V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. | 0.542 |
SFF95874.1 | pcn | SAMN04488063_0927 | SAMN04488063_0304 | DNA polymerase I. | Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.999 |
SFF95874.1 | priL | SAMN04488063_0927 | SAMN04488063_0301 | DNA polymerase I. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.998 |
SFF95874.1 | rfcL | SAMN04488063_0927 | SAMN04488063_2064 | DNA polymerase I. | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. | 0.963 |
SFF95874.1 | top6B | SAMN04488063_0927 | SAMN04488063_2899 | DNA polymerase I. | DNA topoisomerase-6 subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.755 |
SFF95874.1 | topA | SAMN04488063_0927 | SAMN04488063_0747 | DNA polymerase I. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.441 |
atpF | SFF75308.1 | SAMN04488063_0415 | SAMN04488063_0137 | V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Cell division control protein 6; Involved in regulation of DNA replication. | 0.473 |
atpF | SFF95874.1 | SAMN04488063_0415 | SAMN04488063_0927 | V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. | DNA polymerase I. | 0.542 |
atpF | pcn | SAMN04488063_0415 | SAMN04488063_0304 | V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. | Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.675 |
atpF | priL | SAMN04488063_0415 | SAMN04488063_0301 | V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.555 |
atpF | top6A | SAMN04488063_0415 | SAMN04488063_2898 | V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. | DNA topoisomerase-6 subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. | 0.597 |
atpF | top6B | SAMN04488063_0415 | SAMN04488063_2899 | V/A-type H+-transporting ATPase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. | DNA topoisomerase-6 subunit B; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. | 0.664 |