STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFR34081.1KEOPS complex subunit Cgi121. (162 aa)    
Predicted Functional Partners:
SFR62824.1
Bifunctional N6-L-threonylcarbamoyladenine synthase / protein kinase Bud32; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / Tsa [...]
  
 
 
 0.999
hel308
Helicase; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks.
       0.858
SFR37052.1
ACT domain-containing protein.
  
     0.719
SFR55251.1
DNA-directed RNA polymerase, subunit F.
  
     0.669
cofC
Phospholactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
  
     0.661
SFR33794.1
Hypothetical protein.
  
     0.648
SFR34070.1
Ferredoxin.
       0.642
SFR39058.1
Ribbon-helix-helix protein, copG family.
 
     0.642
SFR73969.1
Uncharacterized membrane protein.
  
     0.633
SFR34176.1
Hypothetical protein.
  
     0.626
Your Current Organism:
Halogeometricum rufum
NCBI taxonomy Id: 553469
Other names: CGMCC 1.7736, H. rufum, Halogeometricum rufum Cui et al. 2010, Halosarcina sp. RO1-4, Halosarcina sp. RO1-64, JCM 15770, strain RO1-4
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