STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B7463_g2724Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (956 aa)    
Predicted Functional Partners:
B7463_g5584
Telo_bind domain-containing protein.
    
 0.969
B7463_g453
Uncharacterized protein.
   
 
 0.934
B7463_g1513
VWFA domain-containing protein.
   
 
 0.913
B7463_g2326
SAP domain-containing protein.
    
 
 0.910
B7463_g507
PUA domain-containing protein.
    
 0.908
B7463_g8394
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 
 0.904
B7463_g9949
EST1_DNA_bind domain-containing protein.
   
 
 0.857
B7463_g1399
TruB_N domain-containing protein.
    
 0.853
B7463_g2120
Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.
    
 0.851
B7463_g4363
H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs.
     
 0.839
Your Current Organism:
Scytalidium lignicola
NCBI taxonomy Id: 5539
Other names: CBS 233.57, IMI 062532, MUCL 4172, S. lignicola, UAMH 385
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.