B7463_g2013 protein (Scytalidium lignicola) - STRING interaction network

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Known Interactions

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Predicted Interactions

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Score

B7463_g2013

F-box domain-containing protein. (645 aa)

Predicted Functional Partners:

B7463_g10856

0.937

B7463_g5731

0.928

B7463_g5242

0.836

B7463_g5243

0.836

B7463_g6456

0.748

B7463_g1731

0.745

B7463_g5625

0.739

B7463_g1058

0.691

B7463_g422

0.687

B7463_g9845

0.675

Your Current Organism:

Scytalidium lignicola

NCBI taxonomy Id: 5539
Other names: CBS 233.57, IMI 062532, MUCL 4172, S. lignicola, UAMH 385

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B7463_g1058	B7463_g10856	A0A3E2HPH5	A0A3E2GXK2	PfkB domain-containing protein.	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	0.697
B7463_g1058	B7463_g2013	A0A3E2HPH5	A0A3E2HLV8	PfkB domain-containing protein.	F-box domain-containing protein.	0.691
B7463_g1058	B7463_g5731	A0A3E2HPH5	A0A3E2HB03	PfkB domain-containing protein.	Riboflavin synthase.	0.528
B7463_g1058	B7463_g9845	A0A3E2HPH5	A0A3E2GZF3	PfkB domain-containing protein.	CMP/dCMP-type deaminase domain-containing protein.	0.840
B7463_g10856	B7463_g1058	A0A3E2GXK2	A0A3E2HPH5	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	PfkB domain-containing protein.	0.697
B7463_g10856	B7463_g2013	A0A3E2GXK2	A0A3E2HLV8	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	F-box domain-containing protein.	0.937
B7463_g10856	B7463_g5242	A0A3E2GXK2	A0A3E2HD72	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	PH domain-containing protein.	0.916
B7463_g10856	B7463_g5243	A0A3E2GXK2	A0A3E2HDC9	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	Coronin; Belongs to the WD repeat coronin family.	0.916
B7463_g10856	B7463_g5625	A0A3E2GXK2	A0A3E2HBC9	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	Nucleoside diphosphate kinase.	0.510
B7463_g10856	B7463_g5731	A0A3E2GXK2	A0A3E2HB03	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	Riboflavin synthase.	0.996
B7463_g10856	B7463_g6456	A0A3E2GXK2	A0A3E2H9T2	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	Uncharacterized protein.	0.684
B7463_g10856	B7463_g9845	A0A3E2GXK2	A0A3E2GZF3	6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.	CMP/dCMP-type deaminase domain-containing protein.	0.469
B7463_g1731	B7463_g2013	A0A3E2HMK2	A0A3E2HLV8	Glutamine amidotransferase type-1 domain-containing protein.	F-box domain-containing protein.	0.745
B7463_g1731	B7463_g422	A0A3E2HMK2	A0A3E2HR94	Glutamine amidotransferase type-1 domain-containing protein.	Nucleotide diphosphatase.	0.893
B7463_g1731	B7463_g5242	A0A3E2HMK2	A0A3E2HD72	Glutamine amidotransferase type-1 domain-containing protein.	PH domain-containing protein.	0.614
B7463_g1731	B7463_g5243	A0A3E2HMK2	A0A3E2HDC9	Glutamine amidotransferase type-1 domain-containing protein.	Coronin; Belongs to the WD repeat coronin family.	0.614
B7463_g1731	B7463_g5625	A0A3E2HMK2	A0A3E2HBC9	Glutamine amidotransferase type-1 domain-containing protein.	Nucleoside diphosphate kinase.	0.606
B7463_g1731	B7463_g5731	A0A3E2HMK2	A0A3E2HB03	Glutamine amidotransferase type-1 domain-containing protein.	Riboflavin synthase.	0.472
B7463_g1731	B7463_g6456	A0A3E2HMK2	A0A3E2H9T2	Glutamine amidotransferase type-1 domain-containing protein.	Uncharacterized protein.	0.566
B7463_g2013	B7463_g1058	A0A3E2HLV8	A0A3E2HPH5	F-box domain-containing protein.	PfkB domain-containing protein.	0.691

page 1 of 4

Network Stats

number of nodes:

5

number of edges:

8

average node degree:

3.2

avg. local clustering coefficient:

0.867

expected number of edges:

4

PPI enrichment p-value:

0.052

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0140359

ABC-type transporter activity

3 of 18

2.01

1.16

0.0060

GO:0022804

Active transmembrane transporter activity

4 of 127

1.28

0.68

0.0290

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7683

Type 1 protein exporter

3 of 6

2.48

1.9

0.00029

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

3 of 39

1.67

1.1

0.0051

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1369007

Mitochondrial ABC transporters

2 of 2

2.78

1.04

0.0132

MAP-9754706

Atorvastatin ADME

2 of 6

2.31

1.02

0.0132

MAP-159418

Recycling of bile acids and salts

2 of 5

2.39

1.02

0.0132

MAP-382556

ABC-family proteins mediated transport

3 of 33

1.74

0.94

0.0132

MAP-983170

Antigen Presentation: Folding, assembly and peptide loading of class I MHC

2 of 11

2.04

0.83

0.0284

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00664

ABC transporter transmembrane region

3 of 11

2.22

1.61

0.00088

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR039421

Type 1 protein exporter

3 of 7

2.42

1.64

0.00087

IPR036640

ABC transporter type 1, transmembrane domain superfamily

3 of 11

2.22

1.52

0.0013

IPR011527

ABC transporter type 1, transmembrane domain

3 of 11

2.22

1.52

0.0013

IPR017871

ABC transporter-like, conserved site

3 of 24

1.88

1.2

0.0042

IPR003439

ABC transporter-like, ATP-binding domain

3 of 26

1.85

1.19

0.0044

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

4 of 70

1.54

1.28

0.0012

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