STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
E1ZNZ5_CHLVADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (532 aa)    
Predicted Functional Partners:
E1Z334_CHLVA
Uncharacterized protein.
    
 
 0.831
E1ZP27_CHLVA
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
    
 
 0.799
E1Z204_CHLVA
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.768
E1ZC89_CHLVA
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.768
E1Z4H4_CHLVA
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
 
 0.730
E1ZJR5_CHLVA
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
 
 0.730
E1ZRV4_CHLVA
TOP4c domain-containing protein.
   
 
 0.730
E1ZUQ7_CHLVA
Uncharacterized protein.
   
 
 0.730
E1Z4D2_CHLVA
Uncharacterized protein.
    
 0.713
E1Z6B2_CHLVA
Small ubiquitin-related modifier.
    
 0.713
Your Current Organism:
Chlorella variabilis
NCBI taxonomy Id: 554065
Other names: C. variabilis, Chlorella sp. 211-6, Chlorella sp. Bnd1-ZK, Chlorella sp. Dd1-ZK, Chlorella sp. F36-ZK, Chlorella sp. KM2-ZK, Chlorella sp. NC64A, Chlorella sp. OK1-ZK, Chlorella sp. SAG 211-6, Chlorella sp. So13-ZK, Chlorella sp. Syngen 2-3, SAG 211-6
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