| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KRU21956.1 | KRU22170.1 | AS194_01990 | AS194_09505 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.656 |
| KRU21956.1 | KRU23480.1 | AS194_01990 | AS194_13240 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DnaA regulatory inactivator Hda; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. HdA subfamily. | 0.967 |
| KRU21956.1 | dnaA | AS194_01990 | AS194_01995 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Chromosomal replication initiation protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.981 |
| KRU21956.1 | polA | AS194_01990 | AS194_03030 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.991 |
| KRU21956.1 | recF | AS194_01990 | AS194_01985 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.886 |
| KRU21956.1 | rnpA | AS194_01990 | AS194_02005 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. | 0.625 |
| KRU22170.1 | KRU21956.1 | AS194_09505 | AS194_01990 | ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.656 |
| KRU22170.1 | KRU22720.1 | AS194_09505 | AS194_07565 | ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.454 |
| KRU22170.1 | KRU23630.1 | AS194_09505 | AS194_03745 | ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.537 |
| KRU22170.1 | polA | AS194_09505 | AS194_03030 | ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.608 |
| KRU22170.1 | recF | AS194_09505 | AS194_01985 | ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.627 |
| KRU22170.1 | recR | AS194_09505 | AS194_11935 | ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.511 |
| KRU22170.1 | ruvA | AS194_09505 | AS194_03300 | ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.594 |
| KRU22720.1 | KRU22170.1 | AS194_07565 | AS194_09505 | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | ATP-dependent DNA helicase RecG; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.454 |
| KRU22720.1 | KRU23630.1 | AS194_07565 | AS194_03745 | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.436 |
| KRU22720.1 | polA | AS194_07565 | AS194_03030 | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.622 |
| KRU22720.1 | recF | AS194_07565 | AS194_01985 | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | DNA recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.873 |
| KRU22720.1 | recR | AS194_07565 | AS194_11935 | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.972 |
| KRU22720.1 | ruvA | AS194_07565 | AS194_03300 | DNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.500 |
| KRU23480.1 | KRU21956.1 | AS194_13240 | AS194_01990 | DnaA regulatory inactivator Hda; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. HdA subfamily. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.967 |