| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KRU21279.1 | KRU23257.1 | AS194_03320 | AS194_05360 | Conjugal transfer protein TraR; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.459 |
| KRU22546.1 | KRU23257.1 | AS194_07890 | AS194_05360 | Peptide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.400 |
| KRU22892.1 | KRU23257.1 | AS194_06585 | AS194_05360 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.449 |
| KRU22892.1 | hisI | AS194_06585 | AS194_00490 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.531 |
| KRU23248.1 | KRU23257.1 | AS194_05365 | AS194_05360 | Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.580 |
| KRU23257.1 | KRU21279.1 | AS194_05360 | AS194_03320 | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | Conjugal transfer protein TraR; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.459 |
| KRU23257.1 | KRU22546.1 | AS194_05360 | AS194_07890 | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.400 |
| KRU23257.1 | KRU22892.1 | AS194_05360 | AS194_06585 | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.449 |
| KRU23257.1 | KRU23248.1 | AS194_05360 | AS194_05365 | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.580 |
| KRU23257.1 | dksA | AS194_05360 | AS194_00265 | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | 0.576 |
| KRU23257.1 | hisI | AS194_05360 | AS194_00490 | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | 0.548 |
| KRU23257.1 | map | AS194_05360 | AS194_06535 | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.802 |
| KRU23257.1 | rpmB | AS194_05360 | AS194_01455 | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L28; Required for 70S ribosome assembly; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family. | 0.532 |
| KRU23257.1 | rpmG | AS194_05360 | AS194_01450 | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S ribosomal protein L33; In Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.440 |
| KRU23257.1 | rpsN | AS194_05360 | AS194_11555 | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.714 |
| dksA | KRU23257.1 | AS194_00265 | AS194_05360 | RNA polymerase-binding protein DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression. | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.576 |
| hisI | KRU22892.1 | AS194_00490 | AS194_06585 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.531 |
| hisI | KRU23257.1 | AS194_00490 | AS194_05360 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the N-terminal section; belongs to the PRA-CH family. | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.548 |
| map | KRU23257.1 | AS194_06535 | AS194_05360 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | Cobalamin biosynthesis protein P47K; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.802 |
| map | rpsN | AS194_06535 | AS194_11555 | Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. | 0.964 |