MPER_09865 protein (Moniliophthora perniciosa)

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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Score

MPER_09865

Uncharacterized protein. (192 aa)

Predicted Functional Partners:

LSM8

0.936

MPER_05548

0.918

MPER_02488

0.899

MPER_12071

0.659

MPER_08271

0.634

MPER_00586

0.601

MPER_07026

0.601

MPER_10444

0.601

MPER_08267

0.584

MPER_06221

0.539

Your Current Organism:

Moniliophthora perniciosa

NCBI taxonomy Id: 554373
Other names: M. perniciosa FA553, Moniliophthora perniciosa FA553

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LSM8	MPER_00586	E2LIW7	E2L4G3	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.943
LSM8	MPER_02488	E2LIW7	E2L932	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.923
LSM8	MPER_05548	E2LIW7	E2LGH2	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.999
LSM8	MPER_06221	E2LIW7	E2LI57	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	SFM domain-containing protein.	0.929
LSM8	MPER_07026	E2LIW7	E2LK50	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.943
LSM8	MPER_08271	E2LIW7	E2LN81	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	PRP3 domain-containing protein.	0.998
LSM8	MPER_09865	E2LIW7	E2LS72	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.936
LSM8	MPER_10444	E2LIW7	E2LTM0	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Uncharacterized protein.	0.943
LSM8	MPER_12071	E2LIW7	E2LXQ4	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	Prp31_C domain-containing protein.	0.998
MPER_00586	LSM8	E2L4G3	E2LIW7	Uncharacterized protein.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.943
MPER_00586	MPER_02488	E2L4G3	E2L932	Uncharacterized protein.	Uncharacterized protein.	0.601
MPER_00586	MPER_06221	E2L4G3	E2LI57	Uncharacterized protein.	SFM domain-containing protein.	0.521
MPER_00586	MPER_08271	E2L4G3	E2LN81	Uncharacterized protein.	PRP3 domain-containing protein.	0.850
MPER_00586	MPER_09865	E2L4G3	E2LS72	Uncharacterized protein.	Uncharacterized protein.	0.601
MPER_00586	MPER_12071	E2L4G3	E2LXQ4	Uncharacterized protein.	Prp31_C domain-containing protein.	0.680
MPER_02488	LSM8	E2L932	E2LIW7	Uncharacterized protein.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.923
MPER_02488	MPER_00586	E2L932	E2L4G3	Uncharacterized protein.	Uncharacterized protein.	0.601
MPER_02488	MPER_05548	E2L932	E2LGH2	Uncharacterized protein.	Uncharacterized protein.	0.912
MPER_02488	MPER_06221	E2L932	E2LI57	Uncharacterized protein.	SFM domain-containing protein.	0.539
MPER_02488	MPER_07026	E2L932	E2LK50	Uncharacterized protein.	Uncharacterized protein.	0.601

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

22

average node degree:

4

avg. local clustering coefficient:

0.861

expected number of edges:

13

PPI enrichment p-value:

0.00999

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0070925

Organelle assembly

6 of 126

2.03

3.43

2.58e-08

GO:0051231

Spindle elongation

3 of 3

3.35

8.90e-07

GO:0090307

Mitotic spindle assembly

3 of 10

2.83

2.87

5.25e-06

GO:0007018

Microtubule-based movement

5 of 157

1.85

2.52

2.00e-06

GO:0022607

Cellular component assembly

7 of 390

1.6

2.47

1.13e-07

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003777

Microtubule motor activity

5 of 101

2.04

2.87

8.42e-07

GO:0008017

Microtubule binding

5 of 126

1.95

2.75

9.70e-07

GO:0140657

ATP-dependent activity

6 of 597

1.35

1.55

2.02e-05

GO:0005515

Protein binding

6 of 1282

1.02

0.84

0.0015

GO:0035639

Purine ribonucleoside triphosphate binding

6 of 1740

0.89

0.62

0.0074

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0015630

Microtubule cytoskeleton

9 of 291

1.84

4.43

1.90e-13

GO:0005874

Microtubule

6 of 131

2.01

3.75

2.67e-09

GO:0005815

Microtubule organizing center

4 of 91

1.99

2.53

4.47e-06

GO:0005929

Cilium

3 of 96

1.84

1.59

0.00052

GO:0036064

Ciliary basal body

2 of 28

2.2

1.3

0.0035

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4249

Mixed, incl. Small GTPase superfamily, ARF type, and Spindle pole body-associated protein Vik1/Cik1, microtubule binding domain

5 of 12

2.97

5.41

9.02e-11

CL:4252

Mixed, incl. Ciliary membrane, and Long-chain fatty acid metabolic process

4 of 5

3.25

5.02

7.03e-10

CL:4227

Mixed, incl. Kelch, and Kinesin motor domain, conserved site

6 of 51

2.42

4.98

9.02e-11

CL:4549

Kinesin motor domain, and Microtubule minus-end

4 of 27

2.52

3.62

1.15e-07

CL:4554

Mixed, incl. Chromosome passenger complex, and POLO box domain

2 of 6

2.87

1.77

0.00060

(more ...)

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-983189

Kinesins

4 of 63

2.15

2.43

1.41e-05

MAP-6811434

COPI-dependent Golgi-to-ER retrograde traffic

4 of 87

2.01

2.24

2.45e-05

MAP-8856688

Golgi-to-ER retrograde transport

4 of 96

1.97

2.21

2.45e-05

MAP-983231

Factors involved in megakaryocyte development and platelet production

4 of 99

1.96

2.2

2.45e-05

MAP-6811442

Intra-Golgi and retrograde Golgi-to-ER traffic

4 of 130

1.84

2.0

4.66e-05

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0034464

BBSome

3 of 3

3.35

3.3

1.08e-06

GOCC:0015630

Microtubule cytoskeleton

5 of 202

1.74

2.2

7.26e-06

GOCC:0043226

Organelle

9 of 5058

0.6

0.45

0.0037

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0493

Microtubule

5 of 61

2.26

3.87

1.22e-08

KW-0505

Motor protein

5 of 85

2.12

3.54

2.98e-08

KW-0547

Nucleotide-binding

6 of 670

1.3

1.51

1.29e-05

KW-0067

ATP-binding

5 of 594

1.27

1.26

0.00019

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001752

Kinesin motor domain

5 of 66

2.23

3.23

3.01e-07

IPR036961

Kinesin motor domain superfamily

5 of 81

2.14

3.1

4.02e-07

IPR019821

Kinesin motor domain, conserved site

4 of 44

2.31

2.71

5.29e-06

IPR047149

Kinesin-like protein KIF11-like

2 of 2

3.35

1.67

0.0010

IPR027640

Kinesin-like protein

3 of 61

2.04

1.38

0.0021

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00129

Kinesin motor, catalytic domain. ATPase.

4 of 61

2.17

2.63

5.36e-06

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