MPER_14224 protein (Moniliophthora perniciosa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

MPER_14224

Uncharacterized protein. (114 aa)

Predicted Functional Partners:

MPER_06763

0.999

MPER_07938

0.984

MPER_04893

0.981

MPER_06511

0.981

MPER_10078

0.976

MPER_10149

0.976

MPER_00747

0.947

MPER_01118

0.943

MPER_03738

0.943

MPER_04237

0.943

Your Current Organism:

Moniliophthora perniciosa

NCBI taxonomy Id: 554373
Other names: M. perniciosa FA553, Moniliophthora perniciosa FA553

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structured XML interaction data, according to the 'PSI-MI' data standard

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MPER_00747	MPER_01118	E2L4U5	E2L5R1	Uncharacterized protein.	Uncharacterized protein.	0.923
MPER_00747	MPER_03738	E2L4U5	E2LC24	Uncharacterized protein.	DEP domain-containing protein.	0.923
MPER_00747	MPER_04237	E2L4U5	E2LD98	Uncharacterized protein.	Uncharacterized protein.	0.923
MPER_00747	MPER_04893	E2L4U5	E2LEW1	Uncharacterized protein.	Uncharacterized protein.	0.849
MPER_00747	MPER_06511	E2L4U5	E2LIW0	Uncharacterized protein.	Uncharacterized protein.	0.975
MPER_00747	MPER_06763	E2L4U5	E2LJH6	Uncharacterized protein.	Uncharacterized protein.	0.958
MPER_00747	MPER_10078	E2L4U5	E2LSQ8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.515
MPER_00747	MPER_10149	E2L4U5	E2LSX0	Uncharacterized protein.	Uncharacterized protein.	0.515
MPER_00747	MPER_14224	E2L4U5	E2M2I0	Uncharacterized protein.	Uncharacterized protein.	0.947
MPER_01118	MPER_00747	E2L5R1	E2L4U5	Uncharacterized protein.	Uncharacterized protein.	0.923
MPER_01118	MPER_03738	E2L5R1	E2LC24	Uncharacterized protein.	DEP domain-containing protein.	0.900
MPER_01118	MPER_04237	E2L5R1	E2LD98	Uncharacterized protein.	Uncharacterized protein.	0.900
MPER_01118	MPER_04893	E2L5R1	E2LEW1	Uncharacterized protein.	Uncharacterized protein.	0.797
MPER_01118	MPER_06511	E2L5R1	E2LIW0	Uncharacterized protein.	Uncharacterized protein.	0.969
MPER_01118	MPER_06763	E2L5R1	E2LJH6	Uncharacterized protein.	Uncharacterized protein.	0.934
MPER_01118	MPER_07938	E2L5R1	E2LME4	Uncharacterized protein.	Uncharacterized protein.	0.970
MPER_01118	MPER_10078	E2L5R1	E2LSQ8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.429
MPER_01118	MPER_10149	E2L5R1	E2LSX0	Uncharacterized protein.	Uncharacterized protein.	0.429
MPER_01118	MPER_14224	E2L5R1	E2M2I0	Uncharacterized protein.	Uncharacterized protein.	0.943
MPER_03738	MPER_00747	E2LC24	E2L4U5	DEP domain-containing protein.	Uncharacterized protein.	0.923

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.831

expected number of edges:

11

PPI enrichment p-value:

0.00661

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055085

Transmembrane transport

9 of 245

0.89

0.83

8.52e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

9 of 387

0.69

0.58

0.00044

GO:0016020

Membrane

10 of 698

0.48

0.38

0.0017

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2672

Mixed, incl. ABC transporter, CbiO/EcfA subunit, and Cobalt transport protein

9 of 30

1.8

4.17

5.62e-13

CL:2670

Mixed, incl. Cobalt transport protein, and ABC transporter, CbiO/EcfA subunit

10 of 51

1.61

3.48

4.16e-13

CL:2722

Mixed, incl. Tricarboxylic acid biosynthetic process, and ABC transporter, CbiO/EcfA subunit

4 of 5

2.22

2.84

2.22e-06

CL:2668

Mixed, incl. ABC transporters, and DNA-binding HTH domain, TetR-type

11 of 111

1.32

2.33

7.15e-13

CL:2673

Mixed, incl. ABC transporter, CbiO/EcfA subunit, and Cobalt transport protein

5 of 25

1.62

2.06

6.47e-06

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

10 of 194

1.03

1.28

2.46e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0043190

ATP-binding cassette (ABC) transporter complex

7 of 34

1.64

2.71

1.96e-08

GOCC:0005886

Plasma membrane

9 of 242

0.89

0.94

1.77e-06

GOCC:0032991

Protein-containing complex

8 of 382

0.64

0.52

0.0010

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0067

ATP-binding

6 of 228

0.74

0.41

0.0483

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR015856

ABC transporter, CbiO/EcfA subunit

6 of 10

2.1

3.62

1.55e-08

IPR017871

ABC transporter-like, conserved site

6 of 72

1.24

1.21

0.00022

IPR003439

ABC transporter-like, ATP-binding domain

6 of 90

1.15

1.04

0.00051

IPR003593

AAA+ ATPase domain

6 of 111

1.05

0.88

0.0012

IPR027417

P-loop containing nucleoside triphosphate hydrolase

6 of 224

0.75

0.41

0.0492

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

6 of 109

1.06

0.97

0.00040

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