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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
Toce_0014COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: bbe:BBR47_00780 DNA polymerase III delta' subunit; SPTR: DNA polymerase III delta' subunit. (271 aa)    
Predicted Functional Partners:
Toce_0896
COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790:IPR010372; KEGG: amt:Amet_3057 DNA polymerase III, delta subunit; PFAM: DNA polymerase III delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
 
 
 0.987
Toce_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.982
Toce_0868
DNA polymerase III catalytic subunit, DnaE type; COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR003141:IPR004805:IPR004013:IPR011708:IPR 004365; KEGG: tte:TTE1818 DNA polymerase III DnaE; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directe [...]
  
 0.978
Toce_0096
COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004805:IPR004013:IPR011708:IPR004365:IPR 003141:IPR002226; KEGG: adg:Adeg_0434 DNA polymerase III, alpha subunit; PFAM: DNA polymerase III alpha subunit; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc).
  
 0.977
dnaX
DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
  
0.934
Toce_0015
PSP1 domain protein; COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: gwc:GWCH70_0028 PSP1 domain protein; PFAM: PSP1 domain protein; SPTR: PSP1 domain protein; PFAM: PSP1 C-terminal conserved region.
 
   0.932
polC
DNA polymerase III catalytic subunit, PolC type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
 0.919
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
  
 0.898
Toce_2256
COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: nth:Nther_2915 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb).
 
 
 
 0.854
Toce_0012
Protein of unknown function DUF970; COGs: COG3870 conserved hypothetical protein; InterPro IPR010375; KEGG: sth:STH3257 hypothetical protein; PFAM: protein of unknown function DUF970; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF970).
  
    0.846
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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