Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0015PSP1 domain protein; COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: gwc:GWCH70_0028 PSP1 domain protein; PFAM: PSP1 domain protein; SPTR: PSP1 domain protein; PFAM: PSP1 C-terminal conserved region. (277 aa)    
Predicted Functional Partners:
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
 
    0.944
Toce_0014
COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: bbe:BBR47_00780 DNA polymerase III delta' subunit; SPTR: DNA polymerase III delta' subunit.
 
   0.932
rny
Metal dependent phosphohydrolase; Endoribonuclease that initiates mRNA decay. Belongs to the RNase Y family.
 
  
 0.916
Toce_0013
Protein of unknown function DUF327; COGs: COG1728 conserved hypothetical protein; InterPro IPR005585; KEGG: bha:BH1478 hypothetical protein; PFAM: protein of unknown function DUF327; SPTR: BH1478 protein; PFAM: Protein of unknown function (DUF327).
  
  
 0.865
Toce_0012
Protein of unknown function DUF970; COGs: COG3870 conserved hypothetical protein; InterPro IPR010375; KEGG: sth:STH3257 hypothetical protein; PFAM: protein of unknown function DUF970; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF970).
  
    0.847
recR
DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
      0.769
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
      0.753
Toce_0010
Orn/Lys/Arg decarboxylase major region; COGs: COG1982 Arginine/lysine/ornithine decarboxylase; InterPro IPR000310:IPR008286; KEGG: cya:CYA_1002 Orn/Lys/Arg decarboxylase; PFAM: Orn/Lys/Arg decarboxylase major region; Orn/Lys/Arg decarboxylase domain protein; SPTR: Orn/Lys/Arg decarboxylase; PFAM: Orn/Lys/Arg decarboxylase, C-terminal domain; Orn/Lys/Arg decarboxylase, major domain.
  
    0.735
Toce_0016
Peptidase membrane zinc metallopeptidase putative; COGs: COG2738 Zn-dependent protease; InterPro IPR007395; KEGG: hmo:HM1_2075 conserved hypothetical protein, possible neutral zinc metallopeptidase; PFAM: peptidase membrane zinc metallopeptidase putative; SPTR: Putative uncharacterized protein; PFAM: Putative neutral zinc metallopeptidase.
       0.575
rsmI
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.
 
    0.557
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (16%) [HD]