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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ispE4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (284 aa)    
Predicted Functional Partners:
ispF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP).
 
 
 0.988
ispD
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP).
 
  
 0.987
rsmA
Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.
 
  
 0.909
Toce_0044
Transcriptional regulator, GntR family; COGs: COG1802 Transcriptional regulators; InterPro IPR000524:IPR011711:IPR000485; KEGG: mta:Moth_0073 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain.
    
 0.909
ispG
4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family.
 
  
 0.862
Toce_0045
KEGG: tpd:Teth39_0178 molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein; PFAM: Uncharacterized protein family UPF0007.
       0.829
Toce_0046
Pur operon repressor; COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR010078:IPR015265:IPR000836; KEGG: aoe:Clos_2648 pur operon repressor; PFAM: purine repressor; phosphoribosyltransferase; SPTR: Purine operon repressor, PurR; TIGRFAM: pur operon repressor; PFAM: Phosphoribosyl transferase domain; Bacterial purine repressor, N-terminal; TIGRFAM: pur operon repressor, Bacillus subtilis type.
  
    0.808
Toce_0042
Cyanophycin synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterProIPR011810:IPR005479:IPR013221:IPR004101:IPR 018109:IPR011761; KEGG: tte:TTE2785 cyanophycin synthetase; PFAM: Mur ligase middle domain protein; Carbamoyl-phosphate synthase L chain ATP-binding; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramyl tripeptide synthase; TIGRFAM: cyanophycin synthetase; PFAM: RimK-like ATP-grasp domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Str [...]
  
    0.739
Toce_0779
3D domain protein; COGs: COG3583 conserved hypothetical protein; InterPro IPR011098:IPR007137:IPR010611; KEGG: mta:Moth_0051 hypothetical protein; PFAM: 3D domain protein; G5 domain protein; protein of unknown function DUF348; SPTR: Putative uncharacterized protein; PFAM: 3D domain; Domain of unknown function (DUF348); G5 domain.
     
 0.698
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
  
  
 0.676
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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