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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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mtlDD-mannitol 1-phosphate 5-dehydrogenase; COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118:IPR000669; KEGG: bbe:BBR47_56360 mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: Mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain. (377 aa)    
Predicted Functional Partners:
Toce_0264
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR007737:IPR011608:IPR002178:IPR013011; KEGG: cdf:CD3083 transcription antiterminator; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Putative uncharacterized protein; PFAM: HTH domain; Mga helix-turn-helix domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
  
 0.984
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
 
  
 0.933
Toce_0054
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR011608:IPR002178:IPR013011; KEGG: amt:Amet_4270 transcriptional antiterminator, BglG; PFAM: PRD domain protein; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Transcriptional antiterminator, BglG; PFAM: HTH domain; Mga helix-turn-helix domain; PTS system, Lactose/Cellobiose specific IIB subunit; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
  
 0.932
Toce_0846
Bifunctional phosphoglucose/phosphomannose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR011857:IPR001347:IPR019490; KEGG: ate:Athe_0619 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS); PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase / glucose-6-phosphate isomerase; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/p [...]
    
 0.931
Toce_1986
Transcriptional antiterminator, BglG family; COGs: COG3711 Transcriptional antiterminator; InterPro IPR011608:IPR003501:IPR002178:IPR013011; KEGG: tex:Teth514_0531 transcriptional antiterminator, BglG; PFAM: PRD domain protein; phosphotransferase system lactose/cellobiose-specific IIB subunit; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS modulated transcriptional regulator, MtlR family; PFAM: Mga helix-turn-helix domain; HTH domain; PTS system, Lactose/Cellobiose specific IIB subunit; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase syste [...]
  
 0.902
fbp
Fructose-bisphosphate aldolase; Catalyzes two subsequent steps in gluconeogenesis: the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3- phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P).
     
  0.900
Toce_0541
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterProIPR001034:IPR002178:IPR013011:IPR011608:IPR 007737; KEGG: tit:Thit_0523 PTS modulated transcriptional regulator, MtlR family; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS modulated transcriptional regulator, MtlR family; PFAM: Mga helix-turn-helix domain; HTH domain; PRD domain; PTS system, Lactose/Cellobiose specific IIB subunit; Phosph [...]
 
  
 0.886
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
    
 0.769
Toce_0651
COGs: COG2721 Altronate dehydratase; InterPro IPR007392; KEGG: tpd:Teth39_1677 altronate dehydratase; PFAM: D-galactarate dehydratase/Altronate hydrolase domain protein; PRIAM: Altronate dehydratase; SPTR: Altronate dehydratase; PFAM: D-galactarate dehydratase / Altronate hydrolase, C terminus.
  
  
 0.501
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.468
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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