Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_0060Thioredoxin; COGs: COG3118 Thioredoxin domain-containing protein; InterProIPR005746:IPR013766:IPR006662:IPR017937:IPR 017936; KEGG: rmr:Rmar_0180 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: thioredoxin; PFAM: Thioredoxin; TIGRFAM: thioredoxin; Belongs to the thioredoxin family. (104 aa)    
Predicted Functional Partners:
Toce_0155
COGs: COG0492 Thioredoxin reductase; InterPro IPR005982:IPR013027:IPR000103:IPR008255; KEGG: pth:PTH_1417 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase.
 
 0.990
rho
Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template.
    0.808
Toce_2133
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.798
Toce_0575
Protein-tyrosine phosphatase, low molecular weight; COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: sul:SYO3AOP1_0933 protein tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein ArsC; PFAM: Low molecular weight phosphotyrosine protein phosphatase; TIGRFAM: arsenate reductase (thioredoxin).
  
 
 0.795
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.788
Toce_0907
COGs: COG0459 Chaperonin GroEL (HSP60 family); InterPro IPR002194:IPR017998:IPR002423; KEGG: pth:PTH_0876 chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; SPTR: Chaperonin Cpn60/TCP-1; PFAM: TCP-1/cpn60 chaperonin family.
   
 
 0.788
Toce_1604
COGs: COG0572 Uridine kinase; KEGG: amt:Amet_3643 phosphoribulokinase/uridine kinase; SPTR: Phosphoribulokinase/uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family.
   
 
 0.727
Toce_2067
COGs: COG0394 Protein-tyrosine-phosphatase; InterPro IPR017867:IPR000106; KEGG: dae:Dtox_4179 protein tyrosine phosphatase; PFAM: Protein-tyrosine phosphatase, low molecular weight; SMART: Protein-tyrosine phosphatase, low molecular weight; SPTR: Protein tyrosine phosphatase; PFAM: Low molecular weight phosphotyrosine protein phosphatase.
  
 
 0.695
Toce_0064
Ferric uptake regulator, Fur family; COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: amt:Amet_2333 ferric uptake regulator family protein; PFAM: ferric-uptake regulator; SPTR: Ferric uptake regulator, Fur family; PFAM: Ferric uptake regulator family; Belongs to the Fur family.
  
 
 0.576
Toce_0059
Helix-turn-helix domain protein; InterPro IPR001387:IPR018130; KEGG: adg:Adeg_1668 transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Transcriptional regulator, XRE family; PFAM: Helix-turn-helix.
     
 0.575
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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