Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0086FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain. (849 aa)    
Predicted Functional Partners:
Toce_0536
NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR017896:IPR017900:IPR001949:IPR011538:IPR 019554:IPR019575; KEGG: cce:Ccel_2304 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4 [...]
 
 
 0.994
Toce_0696
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR017896:IPR017900:IPR001949:IPR009737:IPR 011538:IPR019554:IPR019575; KEGG: ate:Athe_1298 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Sucraseferredoxin family protein; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron- [...]
 
 
 0.994
Toce_0242
NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR011538:IPR019554:IPR019575:IPR017900:IPR 017896; KEGG: csc:Csac_0620 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 51 Kd subunit; [...]
 
 
 0.992
Toce_0697
NAD(P)-dependent iron-only hydrogenase catalytic subunit; COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR017896:IPR013352:IPR017900:IPR 019574:IPR004108:IPR003149; KEGG: csc:Csac_1864 hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; iron hydrogenase small subunit; SPTR: Hydrogenase, Fe-only; TIGRFAM: hydrogenase, Fe-only; PFAM: 2Fe-2S iron-sulfur cluster binding domain; Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidor [...]
  
 
 0.989
rnfB
Electron transport complex, RnfABCDGE type, B subunit; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily.
    
 0.964
Toce_0243
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR013027:IPR006963:IPR006656:IPR 000759:IPR017900:IPR006655:IPR017896; KEGG: aoe:Clos_0277 molybdopterin oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: glutamate synt [...]
  
 0.950
Toce_0237
InterPro IPR009501; KEGG: gur:Gura_4126 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised ACR, YkgG family COG1556.
  
 
 0.924
Toce_1146
Conserved hypothetical protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR006058; KEGG: tex:Teth514_1576 hypothetical protein; SPTR: Oxidoreductase FAD-binding domain protein.
  
 
 0.922
Toce_1564
Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
  
 
 0.917
Toce_0785
NAD-dependent formate dehydrogenase catalytic subunit; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; Contains selenocysteine; InterProIPR006478:IPR006655:IPR006963:IPR006656:IPR 006657; KEGG: nth:Nther_0100 formate dehydrogenase, alpha subunit; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Formate dehydrogenase, alpha subunit; TIGRFAM: formate dehydrogenase, alpha subunit; manually curated; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase F [...]
    
 0.915
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.