Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
Toce_0089InterPro IPR000462; KEGG: amt:Amet_3296 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (198 aa)    
Predicted Functional Partners:
Toce_0090
Extracellular solute-binding protein family 1; COGs: COG4134 ABC-type uncharacterized transport system periplasmic component; InterPro IPR006059; KEGG: amt:Amet_3295 putative ABC transporter solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Extracellular solute-binding protein, putative; PFAM: Bacterial extracellular solute-binding protein.
 
     0.954
Toce_0092
Binding-protein-dependent transport systems inner membrane component; COGs: COG1177 ABC-type spermidine/putrescine transport system permease component II; InterPro IPR000515; KEGG: amt:Amet_3293 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
 
    0.928
Toce_0091
COGs: COG1175 ABC-type sugar transport systems permease components; InterPro IPR000515; KEGG: amt:Amet_3294 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component.
 
     0.910
cinA
Competence/damage-inducible protein cinA; COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR001453:IPR008136:IPR008135; KEGG: dtu:Dtur_0064 competence/damage-inducible protein CinA; PFAM: CinA domain protein; molybdopterin binding domain; SPTR: CinA-like protein; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor [...]
  
  
 0.908
Toce_0088
SNARE associated Golgi protein-related protein; COGs: COG0398 conserved hypothetical protein; InterPro IPR015414; KEGG: vfi:VF_A0098 inner membrane protein; PFAM: SNARE associated Golgi protein; SPTR: Putative membrane protein; PFAM: SNARE associated Golgi protein.
 
     0.856
Toce_1222
COGs: COG1426 conserved hypothetical protein; KEGG: tit:Thit_1638 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.806
Toce_0093
ABC transporter related protein; COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR013611:IPR003593:IPR017871; KEGG: amt:Amet_3292 ABC transporter related; PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; SPTR: ABC transporter related; PFAM: ABC transporter; TOBE domain.
 
    0.794
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
  
 0.700
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.674
Toce_0086
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain.
 
  
 0.664
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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