STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0110COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: tit:Thit_2128 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; SPTR: Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase family. (303 aa)    
Predicted Functional Partners:
Toce_1364
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.927
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
 
 
    0.907
Toce_0109
COGs: COG1098 RNA binding protein (contains ribosomal protein S1 domain); InterPro IPR003029; KEGG: pth:PTH_0189 RNA binding protein; PFAM: RNA binding S1 domain protein; SPTR: Predicted RNA binding protein; PFAM: S1 RNA binding domain.
       0.678
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.643
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
  
    0.610
Toce_0108
Septum formation initiator; InterPro IPR007060; KEGG: tye:THEYE_A1003 septum formation initiator family protein; PFAM: Septum formation initiator; SPTR: Septum formation initiator family protein; PFAM: Septum formation initiator.
  
  
 0.533
Toce_0107
Spore cortex biosynthesis protein YabQ; InterPro IPR014242:IPR019074; KEGG: cth:Cthe_2660 hypothetical protein; PFAM: Spore cortex biosynthesis protein, YabQ-like; SPTR: Putative uncharacterized protein; TIGRFAM: spore cortex biosynthesis protein YabQ; PFAM: Spore cortex protein YabQ (Spore_YabQ); TIGRFAM: spore cortex biosynthesis protein YabQ.
       0.531
Toce_0106
Sporulation protein YabP; InterPro IPR012504; KEGG: nth:Nther_0072 sporulation protein YabP; PFAM: YabP family protein; SPTR: Sporulation protein YabP; TIGRFAM: sporulation protein YabP; PFAM: YabP family; TIGRFAM: sporulation protein YabP.
       0.514
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
     
 0.508
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.444
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.