Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
argGCOGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR018223; KEGG: gyc:GYMC61_0760 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (403 aa)    
Predicted Functional Partners:
argH
COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049:IPR000362:IPR003031:IPR020557; KEGG: sth:STH486 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase.
 
 0.999
Toce_1572
Extracellular solute-binding protein family 3; COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638:IPR001320:IPR018313; KEGG: tte:TTE0512 ABC-type amino acid transport system, periplasmic component; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; SPTR: ABC-type amino acid transport system, periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 3.
  
  
 0.933
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.932
Toce_0940
COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: mta:Moth_1785 aminotransferase; PFAM: aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Aminotransferase; PFAM: Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.924
Toce_0605
COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR017932:IPR006426:IPR000583:IPR001962; KEGG: tex:Teth514_2106 asparagine synthetase B; PFAM: asparagine synthase; glutamine amidotransferase class-II; SPTR: Asparagine synthase (Glutamine-hydrolyzing); TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; TIGRFAM: asparagine synthase (glutamine-hydrolyzing).
   
 0.918
Toce_1173
Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR004838; KEGG: ckr:CKR_1346 hypothetical protein; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II.
  
 0.918
Toce_2194
L-asparaginase, type I; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR020827:IPR006034:IPR006033; KEGG: afl:Aflv_2047 L-asparaginase; PFAM: Asparaginase/glutaminase; SPTR: L-asparaginase, type I; TIGRFAM: L-asparaginase, type I; PFAM: Asparaginase; TIGRFAM: L-asparaginases, type I.
   
 
 0.909
Toce_0625
COGs: COG0527 Aspartokinase; InterProIPR018042:IPR005260:IPR001341:IPR001048:IPR 002912; KEGG: chy:CHY_1155 aspartate kinase I; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase; Belongs to the aspartokinase family.
 
 
 0.897
argR
Transcriptional regulator, ArgR family; Regulates arginine biosynthesis genes.
 
  
 0.893
Toce_1474
COGs: COG3643 Glutamate formiminotransferase; InterPro IPR004227:IPR012886:IPR013802; KEGG: sds:SDEG_2057 glutamate formiminotransferase; PFAM: Formiminotransferase domain protein; Formiminotransferase domain protein; PRIAM: Glutamate formimidoyltransferase; SPTR: Glutamate formiminotransferase; TIGRFAM: glutamate formiminotransferase; PFAM: Formiminotransferase domain, N-terminal subdomain; Formiminotransferase domain; TIGRFAM: glutamate formiminotransferase.
     
  0.800
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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