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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0169Small GTP-binding protein; COGs: COG0370 Fe2+ transport system protein B; InterPro IPR005225:IPR002917:IPR006073; KEGG: geo:Geob_2253 ferrous iron transport protein B; PFAM: GTP-binding protein HSR1-related; SPTR: Ferrous iron transport protein B; TIGRFAM: small GTP-binding protein; PFAM: Ferrous iron transport protein B; TIGRFAM: small GTP-binding protein domain. (196 aa)    
Predicted Functional Partners:
Toce_0170
COGs: COG0370 Fe2+ transport system protein B; InterPro IPR011619:IPR011642:IPR011640; KEGG: gem:GM21_2625 ferrous iron transport protein B; PFAM: Ferrous iron transport protein B domain protein; nucleoside recognition domain protein; Ferrous iron transport B domain protein; SPTR: Ferrous iron transport protein B; PFAM: Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB.
     0.994
Toce_0172
FeoA family protein; InterPro IPR007167; KEGG: chy:CHY_2108 FeoA family protein; PFAM: FeoA family protein; SPTR: FeoA family protein; PFAM: FeoA domain.
 
  
 0.973
Toce_0171
KEGG: gem:GM21_2624 hypothetical protein; SPTR: Putative uncharacterized protein.
  
  
 0.892
Toce_1713
FeoA family protein; InterPro IPR007167; KEGG: dae:Dtox_3837 FeoA family protein; PFAM: FeoA family protein; SPTR: Putative uncharacterized protein; PFAM: FeoA domain.
 
  
 0.825
zupT
Zinc/iron permease; Mediates zinc uptake. May also transport other divalent cations; Belongs to the ZIP transporter (TC 2.A.5) family. ZupT subfamily.
     
 0.428
leuS
COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002302:IPR001412:IPR015413:IPR013155; KEGG: chy:CHY_0393 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; tRNA synthetase class I (M); SPTR: Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.420
Toce_2123
ATPase AAA-2 domain protein; COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR018368:IPR001270:IPR004176:IPR 003959:IPR001943:IPR013093:IPR019489; KEGG: tte:TTE2327 ATPase with chaperone activity, ATP-binding subunit; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPases with chaperone activity, ATP-binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associat [...]
     
 0.417
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.416
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
      
 0.412
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
      
 0.407
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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