Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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Toce_0185Arsenite efflux ATP-binding protein ArsA (TC 3.A.4.1.1); COGs: COG0003 ATPase involved in chromosome partitioning; InterPro IPR003348; KEGG: amt:Amet_1830 arsenite-activated ATPase ArsA; PRIAM: Arsenite-transporting ATPase; SPTR: Arsenite-activated ATPase ArsA; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase (arsA). (295 aa)    
Predicted Functional Partners:
Toce_0186
Arsenite efflux ATP-binding protein ArsA (TC 3.A.4.1.1); COGs: COG0003 ATPase involved in chromosome partitioning; InterPro IPR003348; KEGG: amt:Amet_1831 arsenite-activated ATPase ArsA; PRIAM: Arsenite-transporting ATPase; SPTR: Arsenite-activated ATPase ArsA; TIGRFAM: arsenite-activated ATPase ArsA; PFAM: Anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase (arsA).
 
  
 
0.977
Toce_0184
InterPro IPR010712; KEGG: amt:Amet_1829 arsenical resistance operon trans-acting repressor ArsD; PFAM: Arsenical resistance operon trans-acting repressor ArsD; SPTR: Arsenical resistance operon trans-acting repressor ArsD; PFAM: Arsenical resistance operon trans-acting repressor ArsD.
 
   
 0.960
Toce_0183
Transcriptional regulator, ArsR family; COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: cth:Cthe_1112 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family.
     
 0.582
ileS
Isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
    
   0.560
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
   0.527
Toce_0607
Arsenite methyltransferase; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: sus:Acid_4410 arsenite S-adenosylmethyltransferase; PFAM: Methyltransferase type 11; PRIAM: Arsenite methyltransferase; SPTR: Methyltransferase type 11; PFAM: Methyltransferase domain.
 
    
 0.511
Toce_0187
KEGG: amt:Amet_1832 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.509
Toce_1168
TPR repeat-containing protein; COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR001440:IPR013026; KEGG: mth:MTH72 O-linked GlcNAc transferase; PFAM: TPR repeat-containing protein; SPTR: O-linked GlcNAc transferase; PFAM: Coatomer epsilon subunit; Tetratricopeptide repeat.
   
 0.507
Toce_0454
AAA family ATPase, CDC48 subfamily; COGs: COG0464 ATPase of the AAA+ class; InterProIPR003960:IPR005938:IPR003593:IPR003338:IPR 004201:IPR003959; KEGG: mta:Moth_1594 AAA family ATPase, CDC48 subfamily protein; PFAM: AAA ATPase central domain protein; AAA ATPase VAT domain protein; cell division protein 48 CDC48 domain 2; PRIAM: Adenosinetriphosphatase; SMART: AAA ATPase; SPTR: AAA family ATPase, CDC48 subfamily; TIGRFAM: AAA family ATPase, CDC48 subfamily; PFAM: Cell division protein 48 (CDC48), N-terminal domain; ATPase family associated with various cellular activities (AAA); Cell di [...]
 
 
 0.498
Toce_1185
Stage V sporulation protein K; COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR000641:IPR003959:IPR014232; KEGG: drm:Dred_1880 ATPase central domain-containing protein; PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; SPTR: AAA ATPase, central domain protein; TIGRFAM: stage V sporulation protein K; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: probable Rubsico expression protein CbbX; stage V sporulation protein K.
  
 
 0.418
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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