| node1 | node2 | node1 annotation | node2 annotation | score |
| Toce_0199 | Toce_0200 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.945 |
| Toce_0199 | Toce_0968 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR000014:IPR003661:IPR003594:IPR 004358:IPR013656:IPR005467:IPR000700; KEGG: mta:Moth_2494 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP do [...] | 0.802 |
| Toce_0199 | Toce_1109 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689:IPR001543; KEGG: csc:Csac_1269 flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; SPTR: Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM. | 0.756 |
| Toce_0199 | Toce_1110 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR001172:IPR007597:IPR001543:IPR012826; KEGG: tte:TTE1429 flagellar motor switch protein; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; SPTR: Chemotaxis protein CheC, inhibitor of MCP methylation; TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); CheC-like family; TIGRFAM: flagellar motor switch protein FliN. | 0.980 |
| Toce_0199 | Toce_1121 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | CheA signal transduction histidine kinase; COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR003594:IPR002545:IPR004358:IPR 010808:IPR004105:IPR005467; KEGG: tpd:Teth39_1232 CheA signal transduction histidine kinase; PFAM: CheW domain protein; P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; ATP-binding region ATPase domain protein; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SPTR: CheA signal transduction histidine kinase; PFAM: CheW- [...] | 0.762 |
| Toce_0199 | Toce_1300 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.916 |
| Toce_0199 | Toce_1454 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR000014:IPR003660:IPR013767:IPR003661:IPR 003594:IPR005467:IPR000700:IPR004358; KEGG: mta:Moth_0828 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP doma [...] | 0.795 |
| Toce_0199 | Toce_1844 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: amt:Amet_2979 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.841 |
| Toce_0199 | Toce_2004 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: swo:Swol_1680 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.800 |
| Toce_0199 | Toce_2235 | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.752 |
| Toce_0200 | Toce_0199 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | 0.945 |
| Toce_0200 | Toce_0968 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR000014:IPR003661:IPR003594:IPR 004358:IPR013656:IPR005467:IPR000700; KEGG: mta:Moth_2494 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP do [...] | 0.403 |
| Toce_0200 | Toce_1300 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.717 |
| Toce_0200 | Toce_1454 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR000014:IPR003660:IPR013767:IPR003661:IPR 003594:IPR005467:IPR000700:IPR004358; KEGG: mta:Moth_0828 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP doma [...] | 0.402 |
| Toce_0200 | Toce_1844 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: amt:Amet_2979 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.410 |
| Toce_0200 | Toce_2004 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: swo:Swol_1680 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.463 |
| Toce_0200 | Toce_2235 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | COGs: COG5002 Signal transduction histidine kinase; InterProIPR005467:IPR000014:IPR003660:IPR003661:IPR 003594:IPR004358:IPR013767; KEGG: aoe:Clos_2783 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP domain; Histid [...] | 0.403 |
| Toce_0968 | Toce_0199 | COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR000014:IPR003661:IPR003594:IPR 004358:IPR013656:IPR005467:IPR000700; KEGG: mta:Moth_2494 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP do [...] | COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: bcl:ABC3884 stage 0 sporulation protein F; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain. | 0.802 |
| Toce_0968 | Toce_0200 | COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR000014:IPR003661:IPR003594:IPR 004358:IPR013656:IPR005467:IPR000700; KEGG: mta:Moth_2494 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP do [...] | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.403 |
| Toce_0968 | Toce_1300 | COGs: COG5002 Signal transduction histidine kinase; InterProIPR003660:IPR000014:IPR003661:IPR003594:IPR 004358:IPR013656:IPR005467:IPR000700; KEGG: mta:Moth_2494 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: HAMP do [...] | Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. | 0.561 |