Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
Toce_0208Two component transcriptional regulator, LytTR family; COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: adg:Adeg_0898 two component transcriptional regulator, LytTR family; PFAM: response regulator receiver; LytTr DNA-binding region; SMART: response regulator receiver; SPTR: Transcriptional regulator, LytR/AlgR family; PFAM: Response regulator receiver domain; LytTr DNA-binding domain. (254 aa)    
Predicted Functional Partners:
Toce_0207
Signal transduction histidine kinase, LytS; COGs: COG3275 Putative regulator of cell autolysis; InterProIPR011620:IPR003018:IPR010559:IPR003594:IPR 005467; KEGG: amt:Amet_1377 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; 5TM Receptors of the LytS-YhcK type transmembrane region; GAF domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; GAF domain protein; SPTR: Signal transduction histidine kinase, LytS; PFAM: Histidine kinase; 5TMR of 5TMR-LYT; GAF domain; Histidine kinase-, DNA gyrase B-, and H [...]
 0.998
Toce_0545
Histidine kinase; COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003594:IPR018771:IPR010559:IPR004358; KEGG: tex:Teth514_1959 histidine kinase; PFAM: Transcription regulator,histidine kinase sensor-like; histidine kinase internal region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Predicted histidine kinase sensor domain.
 
  
 0.890
Toce_0205
COGs: COG1966 Carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: cbl:CLK_3760 carbon starvation protein CstA; PFAM: carbon starvation protein CstA; SPTR: Carbon starvation protein CstA; PFAM: Carbon starvation protein CstA.
 
   
 0.580
Toce_0206
KEGG: tpd:Teth39_0430 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.553
Toce_0209
Ferredoxin; InterPro IPR001080:IPR017900:IPR017896; KEGG: chy:CHY_1120 ferredoxin; SPTR: Ferredoxin; PFAM: 4Fe-4S binding domain.
       0.466
Toce_0770
Cell envelope-related transcriptional attenuator; COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: tte:TTE0920 transcriptional regulator; PFAM: cell envelope-related transcriptional attenuator; SPTR: Transcriptional regulator; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain.
      
 0.430
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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