Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0218Rubredoxin-type Fe(Cys)4 protein; COGs: COG1773 Rubredoxin; InterPro IPR004039:IPR001052:IPR018527; KEGG: tme:Tmel_0414 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin; PFAM: Rubredoxin. (52 aa)    
Predicted Functional Partners:
Toce_0217
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1251 NAD(P)H-nitrite reductase; InterPro IPR013027:IPR000103; KEGG: hmo:HM1_0433 nad(p)h-nitrite reductase, large subunit protein NirB, putative; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.978
Toce_0215
Flavodoxin/nitric oxide synthase; COGs: COG0426 flavoprotein; InterPro IPR016440:IPR008254; KEGG: fpl:Ferp_1981 flavodoxin/nitric oxide synthase; PFAM: flavodoxin/nitric oxide synthase; SPTR: Flavodoxin/nitric oxide synthase; PFAM: Metallo-beta-lactamase superfamily; Flavodoxin.
 
  
 0.904
Toce_0216
Rubrerythrin; InterPro IPR003251:IPR009040; KEGG: tye:THEYE_A1650 rubrerythrin subfamily; PFAM: Rubrerythrin; SPTR: Rubrerythrin subfamily; PFAM: Rubrerythrin.
  
  
 0.794
Toce_1860
Superoxide reductase; COGs: COG2033 Desulfoferrodoxin; InterPro IPR002742; KEGG: tnp:Tnap_0454 superoxide reductase; PFAM: Desulfoferrodoxin ferrous iron-binding region; PRIAM: Superoxide reductase; SPTR: Superoxide reductase; PFAM: Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin ferrous iron-binding domain.
  
  
 0.776
Toce_0243
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR013027:IPR006963:IPR006656:IPR 000759:IPR017900:IPR006655:IPR017896; KEGG: aoe:Clos_0277 molybdopterin oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: glutamate synt [...]
  
  
 0.574
Toce_0086
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR004017:IPR000759:IPR017900; KEGG: vpa:VP1199 putative glutamate synthase, small chain; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; protein of unknown function DUF224 cysteine-rich region domain protein; SPTR: Pyridine nucleotide-disulphide oxidoreductase family protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Cysteine-rich domain.
     
 0.487
Toce_0871
COGs: COG0469 Pyruvate kinase; InterProIPR001697:IPR018209:IPR015793:IPR015794:IPR 008279; KEGG: tte:TTE1815 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; PEP-utilising protein mobile region; SPTR: Pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase, barrel domain; PEP-utilising enzyme, mobile domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.434
Toce_1793
Rubrerythrin; COGs: COG1592 Rubrerythrin; InterPro IPR003251:IPR004039:IPR009040; KEGG: cpy:Cphy_3121 rubrerythrin; PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubrerythrin; PFAM: Rubrerythrin.
  
  
 0.422
Toce_1823
Rubrerythrin; COGs: COG1592 Rubrerythrin; InterPro IPR003251:IPR004039:IPR009040; KEGG: csc:Csac_2430 rubrerythrin; PFAM: Rubrerythrin; Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubrerythrin; PFAM: Rubrerythrin.
  
  
 0.422
Toce_1626
Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; COGs: COG0450 Peroxiredoxin; InterPro IPR000866:IPR017936; KEGG: dal:Dalk_1204 alkyl hydroperoxide reductase; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family.
  
  
 0.413
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (16%) [HD]