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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Toce_0221methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (174 aa)    
Predicted Functional Partners:
Toce_0259
HhH-GPD family protein; COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR003265; KEGG: bha:BH1749 DNA-3-methyladenine glycosidase; PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: DNA-3-methyladenine glycosidase; PFAM: HhH-GPD superfamily base excision DNA repair protein.
 
  
 0.931
Toce_1469
Domain of unknown function DUF1730; COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR013542:IPR017896:IPR017900; KEGG: gyc:GYMC61_1368 iron-sulfur cluster binding protein; PFAM: domain of unknown function DUF1730; SPTR: Hypothetical conserved protein; PFAM: 4Fe-4S binding domain; Domain of unknown function (DUF1730); TIGRFAM: iron-sulfur cluster binding protein, putative.
      0.907
Toce_0222
Hypothetical protein; KEGG: tte:TTE0062 glycosylase; SPTR: Predicted glycosylase.
       0.697
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.677
Toce_0002
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
    
 
 0.533
Toce_0223
Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin.
       0.448
Toce_1394
PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterProIPR004013:IPR002054:IPR003583:IPR003141:IPR 002008; KEGG: gbm:Gbem_0265 PHP domain protein; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; DNA polymerase X; Helix-hairpin-helix DNA-binding class 1; SPTR: PHP domain protein; PFAM: PHP domain.
     
 0.442
Toce_1731
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR011637; KEGG: hor:Hore_14860 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; DoxX family protein; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; DoxX.
     
 0.418
sigA
RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
   
 
 0.404
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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