| node1 | node2 | node1 annotation | node2 annotation | score |
| Toce_0221 | Toce_0222 | methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Hypothetical protein; KEGG: tte:TTE0062 glycosylase; SPTR: Predicted glycosylase. | 0.697 |
| Toce_0221 | Toce_0223 | methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | 0.448 |
| Toce_0222 | Toce_0221 | Hypothetical protein; KEGG: tte:TTE0062 glycosylase; SPTR: Predicted glycosylase. | methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.697 |
| Toce_0222 | Toce_0223 | Hypothetical protein; KEGG: tte:TTE0062 glycosylase; SPTR: Predicted glycosylase. | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | 0.490 |
| Toce_0223 | Toce_0221 | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | methylated-DNA/protein- cysteinemethyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.448 |
| Toce_0223 | Toce_0222 | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | Hypothetical protein; KEGG: tte:TTE0062 glycosylase; SPTR: Predicted glycosylase. | 0.490 |
| Toce_0223 | Toce_0224 | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: gwc:GWCH70_0298 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system. | 0.417 |
| Toce_0223 | Toce_1146 | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | Conserved hypothetical protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR006058; KEGG: tex:Teth514_1576 hypothetical protein; SPTR: Oxidoreductase FAD-binding domain protein. | 0.623 |
| Toce_0223 | Toce_2079 | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | Shikimate/quinate 5-dehydrogenase; COGs: COG5322 dehydrogenase; InterPro IPR006151; KEGG: tit:Thit_2042 shikimate/quinate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; SPTR: Shikimate/quinate 5-dehydrogenase; PFAM: Shikimate / quinate 5-dehydrogenase. | 0.502 |
| Toce_0223 | Toce_2080 | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | KEGG: tte:TTE2375 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.502 |
| Toce_0224 | Toce_0223 | COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: gwc:GWCH70_0298 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system. | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | 0.417 |
| Toce_1146 | Toce_0223 | Conserved hypothetical protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR006058; KEGG: tex:Teth514_1576 hypothetical protein; SPTR: Oxidoreductase FAD-binding domain protein. | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | 0.623 |
| Toce_2079 | Toce_0223 | Shikimate/quinate 5-dehydrogenase; COGs: COG5322 dehydrogenase; InterPro IPR006151; KEGG: tit:Thit_2042 shikimate/quinate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; SPTR: Shikimate/quinate 5-dehydrogenase; PFAM: Shikimate / quinate 5-dehydrogenase. | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | 0.502 |
| Toce_2079 | Toce_2080 | Shikimate/quinate 5-dehydrogenase; COGs: COG5322 dehydrogenase; InterPro IPR006151; KEGG: tit:Thit_2042 shikimate/quinate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; SPTR: Shikimate/quinate 5-dehydrogenase; PFAM: Shikimate / quinate 5-dehydrogenase. | KEGG: tte:TTE2375 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.994 |
| Toce_2080 | Toce_0223 | KEGG: tte:TTE2375 hypothetical protein; SPTR: Putative uncharacterized protein. | Rubrerythrin; InterPro IPR003251; KEGG: hbu:Hbut_1530 hypothetical protein; PFAM: Rubrerythrin; SPTR: Conserved archaeal protein; PFAM: Rubrerythrin. | 0.502 |
| Toce_2080 | Toce_2079 | KEGG: tte:TTE2375 hypothetical protein; SPTR: Putative uncharacterized protein. | Shikimate/quinate 5-dehydrogenase; COGs: COG5322 dehydrogenase; InterPro IPR006151; KEGG: tit:Thit_2042 shikimate/quinate 5-dehydrogenase; PFAM: Shikimate/quinate 5-dehydrogenase; SPTR: Shikimate/quinate 5-dehydrogenase; PFAM: Shikimate / quinate 5-dehydrogenase. | 0.994 |