| node1 | node2 | node1 annotation | node2 annotation | score |
| Toce_0224 | Toce_0225 | COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: gwc:GWCH70_0298 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system. | COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterProIPR005892:IPR003439:IPR000644:IPR003593:IPR 017871; KEGG: gwc:GWCH70_0297 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; CBS domain containing protein; SMART: AAA ATPase; CBS domain containing protein; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit. | 0.996 |
| Toce_0224 | Toce_0226 | COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: gwc:GWCH70_0298 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system. | COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: gyc:GYMC61_1174 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | 0.999 |
| Toce_0224 | Toce_0227 | COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: gwc:GWCH70_0298 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system. | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | 0.418 |
| Toce_0225 | Toce_0224 | COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterProIPR005892:IPR003439:IPR000644:IPR003593:IPR 017871; KEGG: gwc:GWCH70_0297 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; CBS domain containing protein; SMART: AAA ATPase; CBS domain containing protein; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit. | COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: gwc:GWCH70_0298 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system. | 0.996 |
| Toce_0225 | Toce_0226 | COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterProIPR005892:IPR003439:IPR000644:IPR003593:IPR 017871; KEGG: gwc:GWCH70_0297 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; CBS domain containing protein; SMART: AAA ATPase; CBS domain containing protein; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit. | COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: gyc:GYMC61_1174 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | 0.997 |
| Toce_0225 | Toce_0227 | COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterProIPR005892:IPR003439:IPR000644:IPR003593:IPR 017871; KEGG: gwc:GWCH70_0297 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; CBS domain containing protein; SMART: AAA ATPase; CBS domain containing protein; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit. | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | 0.453 |
| Toce_0226 | Toce_0224 | COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: gyc:GYMC61_1174 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: gwc:GWCH70_0298 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system. | 0.999 |
| Toce_0226 | Toce_0225 | COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: gyc:GYMC61_1174 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterProIPR005892:IPR003439:IPR000644:IPR003593:IPR 017871; KEGG: gwc:GWCH70_0297 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; CBS domain containing protein; SMART: AAA ATPase; CBS domain containing protein; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit. | 0.997 |
| Toce_0226 | Toce_0227 | COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: gyc:GYMC61_1174 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | 0.470 |
| Toce_0227 | Toce_0224 | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210; KEGG: gwc:GWCH70_0298 substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate-binding region of ABC-type glycine betaine transport system; SPTR: Substrate-binding region of ABC-type glycine betaine transport system; PFAM: Substrate binding domain of ABC-type glycine betaine transport system. | 0.418 |
| Toce_0227 | Toce_0225 | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterProIPR005892:IPR003439:IPR000644:IPR003593:IPR 017871; KEGG: gwc:GWCH70_0297 glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter related; CBS domain containing protein; SMART: AAA ATPase; CBS domain containing protein; SPTR: Glycine betaine/L-proline ABC transporter, ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter, ATPase subunit; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit. | 0.453 |
| Toce_0227 | Toce_0226 | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | COGs: COG1174 ABC-type proline/glycine betaine transport systems permease component; InterPro IPR000515; KEGG: gyc:GYMC61_1174 binding-protein-dependent transport systems inner membrane component; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component. | 0.470 |
| Toce_0227 | Toce_0228 | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterPro IPR007525:IPR017900:IPR017896; KEGG: dps:DPPB80 related to F420H2-dehydrogenase, beta subunit; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: 4Fe-4S binding domain; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus. | 0.535 |
| Toce_0227 | Toce_0372 | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: tte:TTE2335 diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; GAF domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); TIGRFAM: diguanylate cyclase; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | 0.731 |
| Toce_0227 | Toce_0460 | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789:IPR013972; KEGG: cbe:Cbei_4174 response regulator receiver; PFAM: YcbB domain protein; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; YcbB domain. | 0.798 |
| Toce_0227 | Toce_0473 | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | COGs: COG2206 HD-GYP domain; InterPro IPR000160:IPR006674; KEGG: nth:Nther_2110 diguanylate cyclase and metal dependent phosphohydrolase; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PFAM: HD domain; GGDEF domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain. | 0.498 |
| Toce_0228 | Toce_0227 | COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterPro IPR007525:IPR017900:IPR017896; KEGG: dps:DPPB80 related to F420H2-dehydrogenase, beta subunit; PFAM: coenzyme F420 hydrogenase/dehydrogenase beta subunit domain protein; SPTR: Putative uncharacterized protein; manually curated; PFAM: 4Fe-4S binding domain; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus. | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | 0.535 |
| Toce_0372 | Toce_0227 | Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: tte:TTE2335 diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; GAF domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); TIGRFAM: diguanylate cyclase; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | PAS fold domain protein; InterPro IPR013767:IPR000014; KEGG: pgn:PGN_0746 hypothetical protein; PFAM: PAS fold domain protein; SMART: PAS domain containing protein; SPTR: Putative uncharacterized protein; PFAM: PAS fold. | 0.731 |
| Toce_0372 | Toce_0460 | Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: tte:TTE2335 diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; GAF domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); TIGRFAM: diguanylate cyclase; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | Response regulator receiver protein; COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789:IPR013972; KEGG: cbe:Cbei_4174 response regulator receiver; PFAM: YcbB domain protein; response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver; PFAM: Response regulator receiver domain; YcbB domain. | 0.744 |
| Toce_0372 | Toce_0473 | Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR003018; KEGG: tte:TTE2335 diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; GAF domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; GAF domain protein; SPTR: Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF); TIGRFAM: diguanylate cyclase; PFAM: GAF domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain. | COGs: COG2206 HD-GYP domain; InterPro IPR000160:IPR006674; KEGG: nth:Nther_2110 diguanylate cyclase and metal dependent phosphohydrolase; PFAM: GGDEF domain containing protein; metal-dependent phosphohydrolase HD sub domain; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase and metal dependent phosphohydrolase; TIGRFAM: diguanylate cyclase; PFAM: HD domain; GGDEF domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain. | 0.797 |