Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0240KEGG: tpd:Teth39_1732 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF322). (274 aa)    
Predicted Functional Partners:
Toce_1051
Thioesterase superfamily protein; InterPro IPR001034:IPR006683:IPR017275; KEGG: tit:Thit_1285 protein for fatty acid biosynthesis transcriptional regulation; PFAM: thioesterase superfamily protein; regulatory protein DeoR; SPTR: Protein for fatty acid biosynthesis transcriptional regulation; manually curated; PFAM: Thioesterase superfamily; DeoR-like helix-turn-helix domain.
 
   
 0.784
Toce_0241
COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: csc:Csac_0619 NADH dehydrogenase (ubiquinone), 24 kDa subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; SPTR: NADH dehydrogenase (Ubiquinone), 24 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit.
       0.558
Toce_0242
NADH dehydrogenase (quinone); COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR011538:IPR019554:IPR019575:IPR017900:IPR 017896; KEGG: csc:Csac_0620 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 51 Kd subunit; [...]
       0.521
Toce_0243
FAD-dependent pyridine nucleotide-disulfide oxidoreductase; COGs: COG3383 Uncharacterized anaerobic dehydrogenase; InterProIPR001041:IPR013027:IPR006963:IPR006656:IPR 000759:IPR017900:IPR006655:IPR017896; KEGG: aoe:Clos_0277 molybdopterin oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; ferredoxin; molybdopterin oxidoreductase Fe4S4 region; molybdopterin oxidoreductase; SPTR: Molybdopterin oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Molybdopterin oxidoreductase; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: glutamate synt [...]
       0.485
Toce_1312
Protein of unknown function DUF2273; InterPro IPR018730; KEGG: cce:Ccel_1906 hypothetical protein; PFAM: Protein of unknown function DUF2273; SPTR: Putative uncharacterized protein; PFAM: Small integral membrane protein (DUF2273).
 
     0.477
Toce_0239
Copper amine oxidase domain protein; COGs: COG3858 glycosyl hydrolase; InterPro IPR012854:IPR001223:IPR011583:IPR001579; KEGG: swo:Swol_1871 glycosyl hydrolase-like protein; PFAM: copper amine oxidase domain protein; glycoside hydrolase family 18; SMART: chitinase II; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain; Glycosyl hydrolases family 18; Belongs to the glycosyl hydrolase 18 family.
       0.473
Toce_1604
COGs: COG0572 Uridine kinase; KEGG: amt:Amet_3643 phosphoribulokinase/uridine kinase; SPTR: Phosphoribulokinase/uridine kinase; PFAM: Phosphoribulokinase / Uridine kinase family.
  
     0.446
Toce_1037
DAK2 domain fusion protein YloV; COGs: COG1461 kinase related to dihydroxyacetone kinase; InterPro IPR004007:IPR019986; KEGG: amt:Amet_2771 Dak phosphatase; PFAM: Dak phosphatase; SPTR: Dak phosphatase; TIGRFAM: DAK2 domain fusion protein YloV; PFAM: DAK2 domain; TIGRFAM: DAK2 domain fusion protein YloV.
  
  
 0.443
Toce_0238
COGs: COG5423 metal-binding protein; InterPro IPR019271; KEGG: pth:PTH_2051 hypothetical protein; PFAM: Protein of unknown function DUF2284, metal-binding; SPTR: Putative uncharacterized protein; PFAM: Predicted metal-binding protein (DUF2284).
       0.430
Toce_1373
KEGG: tte:TTE1185 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.426
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (8%) [HD]