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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
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kuDNA end-binding protein Ku; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (274 aa)    
Predicted Functional Partners:
Toce_0250
DNA polymerase LigD, polymerase domain protein; COGs: COG3285 eukaryotic-type DNA primase; InterPro IPR014145:IPR002755; KEGG: swo:Swol_1124 hypothetical protein; PFAM: DNA primase small subunit; SPTR: Putative uncharacterized protein; TIGRFAM: DNA polymerase LigD, polymerase domain protein; TIGRFAM: DNA ligase D; DNA polymerase LigD, polymerase domain.
 
  
 0.935
Toce_0249
COGs: COG1793 ATP-dependent DNA ligase; InterPro IPR012310:IPR016059; KEGG: swo:Swol_1123 DNA ligase, putative; PFAM: ATP dependent DNA ligase; SPTR: DNA ligase, putative; PFAM: ATP dependent DNA ligase domain; ATP dependent DNA ligase C terminal region; TIGRFAM: DNA polymerase LigD, ligase domain.
 
  
 0.919
Toce_0247
2,3-diketo-5-methylthio-1-phosphopentanephosphat ase; COGs: COG4359 conserved hypothetical protein; InterPro IPR006384:IPR006383:IPR005834; KEGG: pth:PTH_0926 hypothetical protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Uncharacterized conserved protein; TIGRFAM: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Putative Phosphatase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
       0.447
Toce_0782
Protein of unknown function DUF421; COGs: COG2323 membrane protein; InterPro IPR007353; KEGG: hmo:HM1_1754 duf421 protein; PFAM: protein of unknown function DUF421; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF421).
 
     0.404
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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