Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0251COGs: COG0644 Dehydrogenase (flavoprotein); InterPro IPR003953:IPR003042; KEGG: nth:Nther_1774 FAD dependent oxidoreductase; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: FAD dependent oxidoreductase; PFAM: FAD binding domain. (355 aa)    
Predicted Functional Partners:
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
 
  
 0.787
Toce_1368
COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593; KEGG: sth:STH2441 putative chelatase; PRIAM: Magnesium chelatase; SMART: AAA ATPase; SPTR: Putative chelatase.
  
  
 0.766
Toce_1367
Von Willebrand factor type A; COGs: COG1240 Mg-chelatase subunit ChlD; InterPro IPR002035; KEGG: nth:Nther_2026 von Willebrand factor type A; PFAM: von Willebrand factor type A; SMART: von Willebrand factor type A; SPTR: Von Willebrand factor, type A; PFAM: von Willebrand factor type A domain.
 
  
 0.628
Toce_0487
O-antigen polymerase; InterPro IPR019734:IPR013026:IPR007016; KEGG: tte:TTE0644 TPR repeat-containing protein; PFAM: O-antigen polymerase; SPTR: TPR-repeat-containing proteins; PFAM: O-Antigen ligase.
 
     0.609
Toce_0878
ErfK/YbiS/YcfS/YnhG family protein; COGs: COG1376 conserved hypothetical protein; InterPro IPR005490; KEGG: cbi:CLJ_B0018 ErfK/YbiS/YcfS/YnhG family protein; PFAM: ErfK/YbiS/YcfS/YnhG family protein; SPTR: ErfK/YbiS/YcfS/YnhG family protein; PFAM: L,D-transpeptidase catalytic domain.
  
     0.608
Toce_0254
Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460; KEGG: tte:TTE1967 cell division protein FtsI/penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein transpeptidase; PFAM: Penicillin binding protein transpeptidase domain.
     
 0.559
Toce_0253
Cell cycle protein; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: tpd:Teth39_0572 cell cycle protein; PFAM: cell cycle protein; SPTR: Cell cycle protein; PFAM: Cell cycle protein; Belongs to the SEDS family.
     
 0.553
Toce_0252
COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: tit:Thit_1769 FHA domain containing protein; PFAM: Forkhead-associated protein; SMART: Forkhead-associated protein; SPTR: FHA domain containing protein; PFAM: FHA domain.
       0.544
Toce_0696
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR017896:IPR017900:IPR001949:IPR009737:IPR 011538:IPR019554:IPR019575; KEGG: ate:Athe_1298 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Sucraseferredoxin family protein; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron- [...]
  
  
 0.528
Toce_1348
COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR006371:IPR000537; KEGG: gym:GYMC10_0625 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase; Belongs to the UbiA prenyltransferase family.
  
  
 0.508
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (10%) [HD]