Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Toce_0270COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: pth:PTH_1415 metal-dependent hydrolase; SPTR: UPF0173 metal-dependent hydrolase PTH_1415; PFAM: Metallo-beta-lactamase superfamily; Belongs to the UPF0173 family. (230 aa)    
Predicted Functional Partners:
cutC
CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family.
       0.473
Toce_0269
COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR003501:IPR013012; KEGG: tai:Taci_0332 phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: Phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit; TIGRFAM: PTS system, lactose/cellobiose family IIB component.
       0.436
Toce_0267
PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
       0.412
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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