| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0103 | Toce_1364 | Toce_0103 | Toce_1364 | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551:IPR004518; KEGG: tpd:Teth39_0248 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.927 |
| Toce_0103 | Toce_1992 | Toce_0103 | Toce_1992 | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551:IPR004518; KEGG: tpd:Teth39_0248 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833:IPR005144; KEGG: ate:Athe_0548 anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | 0.907 |
| Toce_0103 | folE2 | Toce_0103 | Toce_0571 | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551:IPR004518; KEGG: tpd:Teth39_0248 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | GTP cyclohydrolase I; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
| Toce_0103 | moaA | Toce_0103 | Toce_0274 | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551:IPR004518; KEGG: tpd:Teth39_0248 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.820 |
| Toce_0103 | ndk | Toce_0103 | Toce_1649 | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551:IPR004518; KEGG: tpd:Teth39_0248 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
| Toce_0103 | ribBA | Toce_0103 | Toce_1693 | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551:IPR004518; KEGG: tpd:Teth39_0248 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.819 |
| Toce_0272 | Toce_0273 | Toce_0272 | Toce_0273 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.986 |
| Toce_0272 | Toce_0276 | Toce_0272 | Toce_0276 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453:IPR008284; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. | 0.999 |
| Toce_0272 | moaA | Toce_0272 | Toce_0274 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.989 |
| Toce_0272 | moaC | Toce_0272 | Toce_0275 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.990 |
| Toce_0273 | Toce_0272 | Toce_0273 | Toce_0272 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.986 |
| Toce_0273 | Toce_0276 | Toce_0273 | Toce_0276 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453:IPR008284; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. | 0.999 |
| Toce_0273 | moaA | Toce_0273 | Toce_0274 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.980 |
| Toce_0273 | moaC | Toce_0273 | Toce_0275 | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.966 |
| Toce_0276 | Toce_0272 | Toce_0276 | Toce_0272 | Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453:IPR008284; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.999 |
| Toce_0276 | Toce_0273 | Toce_0276 | Toce_0273 | Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453:IPR008284; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. | Molybdopterin molybdochelatase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.999 |
| Toce_0276 | moaA | Toce_0276 | Toce_0274 | Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453:IPR008284; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.991 |
| Toce_0276 | moaC | Toce_0276 | Toce_0275 | Molybdenum cofactor synthesis domain protein; COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453:IPR008284; KEGG: ddf:DEFDS_0070 hypothetical protein; PFAM: molybdopterin binding domain; MOSC domain containing protein; SPTR: Putative uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain. | GTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.999 |
| Toce_1364 | Toce_0103 | Toce_1364 | Toce_0103 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR011551:IPR004518; KEGG: tpd:Teth39_0248 MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG family protein; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein. | 0.927 |
| Toce_1364 | Toce_1992 | Toce_1364 | Toce_1992 | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR012833:IPR005144; KEGG: ate:Athe_0548 anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase. | 0.907 |