Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Toce_0287TPR repeat-containing protein; InterPro IPR001440:IPR019734:IPR013026; KEGG: dae:Dtox_2626 TPR repeat-containing protein; PFAM: TPR repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat. (395 aa)    
Predicted Functional Partners:
Toce_0286
COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: dae:Dtox_2624 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
 
     0.775
Toce_0040
Spore coat assembly protein SafA; InterPro IPR014248:IPR018392:IPR002482; KEGG: hor:Hore_21410 peptidoglycan-binding LysM; PFAM: Peptidoglycan-binding lysin domain; SMART: Peptidoglycan-binding LysM; SPTR: Peptidoglycan-binding LysM; TIGRFAM: spore coat assembly protein SafA; PFAM: LysM domain; TIGRFAM: spore coat assembly protein SafA.
 
  
 0.743
Toce_1168
TPR repeat-containing protein; COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR001440:IPR013026; KEGG: mth:MTH72 O-linked GlcNAc transferase; PFAM: TPR repeat-containing protein; SPTR: O-linked GlcNAc transferase; PFAM: Coatomer epsilon subunit; Tetratricopeptide repeat.
   
 
 0.708
gyrA
DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
  
  
 0.697
Toce_1588
COGs: COG0438 Glycosyltransferase; InterProIPR001296:IPR013216:IPR001173:IPR019734:IPR 013026:IPR000276; KEGG: tnp:Tnap_0554 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; Methyltransferase type 11; glycosyl transferase group 1; SMART: Tetratricopeptide repeat; SPTR: Glycosyl transferase family 2; PFAM: Methyltransferase domain; Glycosyl transferases group 1; Glycosyl transferase family 2.
  
  
 0.658
ribBA
GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.587
Toce_0877
KEGG: tpd:Teth39_0292 hypothetical protein; SPTR: Putative uncharacterized protein.
 
   
 0.582
Toce_0285
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dae:Dtox_2625 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal.
 
   
 0.563
Toce_0544
Copper amine oxidase domain protein; COGs: COG3858 glycosyl hydrolase; InterPro IPR012854:IPR001223; KEGG: tit:Thit_2291 copper amine oxidase domain protein; PFAM: copper amine oxidase domain protein; glycoside hydrolase family 18; SPTR: Copper amine oxidase domain protein; PFAM: Copper amine oxidase N-terminal domain; Glycosyl hydrolases family 18.
  
     0.548
Toce_0279
COGs: COG2764 conserved hypothetical protein; KEGG: cth:Cthe_0331 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily.
  
    0.530
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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