Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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Toce_0288Methicillin resistance protein; COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: mta:Moth_2408 methicillin resistance protein; PFAM: Methicillin resistance protein; SPTR: Methicillin resistance protein; PFAM: FemAB family. (368 aa)    
Predicted Functional Partners:
Toce_0289
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
 
   
 0.820
Toce_1592
DegT/DnrJ/EryC1/StrS aminotransferase; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tte:TTE0651 cell wall biogenesis regulatory protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; Belongs to the DegT/DnrJ/EryC1 family.
      0.632
Toce_0042
Cyanophycin synthetase; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterProIPR011810:IPR005479:IPR013221:IPR004101:IPR 018109:IPR011761; KEGG: tte:TTE2785 cyanophycin synthetase; PFAM: Mur ligase middle domain protein; Carbamoyl-phosphate synthase L chain ATP-binding; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramyl tripeptide synthase; TIGRFAM: cyanophycin synthetase; PFAM: RimK-like ATP-grasp domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Str [...]
     
 0.567
Toce_0287
TPR repeat-containing protein; InterPro IPR001440:IPR019734:IPR013026; KEGG: dae:Dtox_2626 TPR repeat-containing protein; PFAM: TPR repeat-containing protein; SPTR: TPR repeat-containing protein; PFAM: Tetratricopeptide repeat.
       0.498
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
   
  
 0.491
Toce_0202
InterPro IPR004518; KEGG: tpd:Teth39_0442 MazG nucleotide pyrophosphohydrolase; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: MazG nucleotide pyrophosphohydrolase; PFAM: MazG nucleotide pyrophosphohydrolase domain.
  
     0.467
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
      
 0.466
Toce_0478
Protein of unknown function DUF1659; InterPro IPR012454; KEGG: mta:Moth_1793 hypothetical protein; PFAM: protein of unknown function DUF1659; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1659).
  
     0.463
Toce_0474
KEGG: amt:Amet_0695 hypothetical protein; SPTR: Putative uncharacterized protein.
  
     0.433
murJ
Integral membrane protein MviN; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
 
     0.417
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
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