Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Toce_0292PTS system transcriptional activator; COGs: COG1221 Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain; InterProIPR002078:IPR011608:IPR004701:IPR003593:IPR 002464; KEGG: cbk:CLL_A3361 transcriptional regulatory protein LevR; PFAM: sigma-54 factor interaction domain-containing protein; PRD domain protein; PTS system fructose subfamily IIA component; SMART: AAA ATPase; SPTR: PTS system transcriptional activator; PFAM: PTS system fructose IIA component; Sigma-54 interaction domain; PRD domain. (878 aa)    
Predicted Functional Partners:
Toce_1856
COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: pth:PTH_2724 DNA-directed RNA polymerase specialized sigma subunit, sigma54-like protein; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; PFAM: Sigma-54 factor, Activator interacting domain (AID); Sigma-54, DNA binding domain; Sigma-54 factor, core binding domain; TIGRFAM: RNA polymeras [...]
 
 
 
 0.895
Toce_1903
COGs: COG3715 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIC; InterPro IPR004700; KEGG: tit:Thit_0166 phosphotransferase system PTS sorbose-specific IIC subunit; PFAM: phosphotransferase system PTS sorbose-specific IIC subunit; SPTR: Phosphotransferase system PTS sorbose-specific IIC subunit; PFAM: PTS system sorbose-specific iic component.
 
  
 0.748
Toce_1986
Transcriptional antiterminator, BglG family; COGs: COG3711 Transcriptional antiterminator; InterPro IPR011608:IPR003501:IPR002178:IPR013011; KEGG: tex:Teth514_0531 transcriptional antiterminator, BglG; PFAM: PRD domain protein; phosphotransferase system lactose/cellobiose-specific IIB subunit; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS modulated transcriptional regulator, MtlR family; PFAM: Mga helix-turn-helix domain; HTH domain; PTS system, Lactose/Cellobiose specific IIB subunit; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase syste [...]
 
   
 0.666
Toce_0264
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR007737:IPR011608:IPR002178:IPR013011; KEGG: cdf:CD3083 transcription antiterminator; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Putative uncharacterized protein; PFAM: HTH domain; Mga helix-turn-helix domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2.
 
   
 0.628
Toce_0541
Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterProIPR001034:IPR002178:IPR013011:IPR011608:IPR 007737; KEGG: tit:Thit_0523 PTS modulated transcriptional regulator, MtlR family; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS modulated transcriptional regulator, MtlR family; PFAM: Mga helix-turn-helix domain; HTH domain; PRD domain; PTS system, Lactose/Cellobiose specific IIB subunit; Phosph [...]
 
   
 0.604
Toce_1984
COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR003501:IPR013012; KEGG: tit:Thit_0585 phosphotransferase system lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: Phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit.
 
     0.580
Toce_1982
COGs: COG1447 Phosphotransferase system cellobiose-specific component IIA; InterPro IPR003188; KEGG: tpd:Teth39_1697 phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit; PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; SPTR: Phosphotransferase system cellobiose-specific component IIA; PFAM: PTS system, Lactose/Cellobiose specific IIA subunit.
 
   
 0.563
Toce_0295
COGs: COG3444 Phosphotransferase system mannose/fructose/N-acetylgalactosamine-specific component IIB; InterPro IPR004720:IPR000209; KEGG: cbk:CLL_A3359 PTS system sorbose subfamily IIB component; PFAM: PTS system sorbose subfamily IIB component; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Protein-N(Pi)-phosphohistidine--sugar phosphotransferase; PFAM: PTS system sorbose subfamily IIB component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIB component.
 
   
 0.560
Toce_0294
COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR004701; KEGG: cbk:CLL_A3360 PTS system fructose IIA component; PFAM: PTS system fructose subfamily IIA component; SPTR: PTS system fructose subfamily IIA component; PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component.
 
  
 0.555
Toce_1983
PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
     0.546
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.