STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
comB2-phosphosulfolactate phosphatase; COGs: COG2045 Phosphosulfolactate phosphohydrolase; InterPro IPR005238; KEGG: cac:CAC3233 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulfolactate phosphatase; SPTR: Probable 2-phosphosulfolactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase; PFAM: 2-phosphosulpholactate phosphatase; TIGRFAM: 2-phosphosulfolactate phosphatase; Belongs to the ComB family. (246 aa)    
Predicted Functional Partners:
Toce_0302
DNA polymerase beta domain protein region; InterPro IPR002934:IPR007842; KEGG: pth:PTH_0436 hypothetical protein; PFAM: DNA polymerase beta domain protein region; HEPN domain protein; SPTR: Hypothetical membrane protein; PFAM: Nucleotidyltransferase domain.
       0.636
Toce_0303
Integrase catalytic region; InterPro IPR001584; KEGG: adg:Adeg_0459 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain.
       0.477
Toce_0895
DNA internalization-related competence protein ComEC/Rec2; COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004797:IPR004477; KEGG: tit:Thit_0878 DNA internalization-related competence protein ComEC/Rec2; PFAM: ComEC/Rec2-related protein; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; ComEC/Rec2-related protein; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2.
      
 0.424
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
       0.422
Your Current Organism:
Thermosediminibacter oceani
NCBI taxonomy Id: 555079
Other names: T. oceani DSM 16646, Thermosediminibacter oceani DSM 16646, Thermosediminibacter oceani JW/IW-1228P, Thermosediminibacter oceani str. DSM 16646, Thermosediminibacter oceani strain DSM 16646
Server load: low (36%) [HD]