| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0002 | Toce_0200 | Toce_0002 | Toce_0200 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.511 |
| Toce_0002 | Toce_0324 | Toce_0002 | Toce_0324 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | 0.666 |
| Toce_0002 | Toce_0459 | Toce_0002 | Toce_0459 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467:IPR003594:IPR004358; KEGG: cbe:Cbei_4175 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.511 |
| Toce_0002 | Toce_0694 | Toce_0002 | Toce_0694 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR004358; KEGG: cpy:Cphy_3802 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.511 |
| Toce_0002 | Toce_1945 | Toce_0002 | Toce_1945 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Helicase domain protein; InterPro IPR014001:IPR001650:IPR000330:IPR014021; KEGG: tex:Teth514_1830 helicase domain-containing protein; PFAM: helicase domain protein; SNF2-related protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | 0.949 |
| Toce_0200 | Toce_0002 | Toce_0200 | Toce_0002 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.511 |
| Toce_0200 | Toce_0324 | Toce_0200 | Toce_0324 | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | 0.657 |
| Toce_0305 | Toce_0324 | Toce_0305 | Toce_0324 | COGs: COG1930 ABC-type cobalt transport system periplasmic component; InterPro IPR000209; KEGG: tit:Thit_0369 cobalt transport protein CbiN; SPTR: Cobalt transport protein CbiN; PFAM: Cobalt transport protein component CbiN; TIGRFAM: cobalt transport protein. | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | 0.478 |
| Toce_0324 | Toce_0002 | Toce_0324 | Toce_0002 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.666 |
| Toce_0324 | Toce_0200 | Toce_0324 | Toce_0200 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: bld:BLi00981 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain. | 0.657 |
| Toce_0324 | Toce_0305 | Toce_0324 | Toce_0305 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | COGs: COG1930 ABC-type cobalt transport system periplasmic component; InterPro IPR000209; KEGG: tit:Thit_0369 cobalt transport protein CbiN; SPTR: Cobalt transport protein CbiN; PFAM: Cobalt transport protein component CbiN; TIGRFAM: cobalt transport protein. | 0.478 |
| Toce_0324 | Toce_0325 | Toce_0324 | Toce_0325 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | 0.566 |
| Toce_0324 | Toce_0459 | Toce_0324 | Toce_0459 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | COGs: COG0642 Signal transduction histidine kinase; InterPro IPR005467:IPR003594:IPR004358; KEGG: cbe:Cbei_4175 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.657 |
| Toce_0324 | Toce_0694 | Toce_0324 | Toce_0694 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | Histidine kinase; COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR004358; KEGG: cpy:Cphy_3802 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. | 0.657 |
| Toce_0324 | Toce_0853 | Toce_0324 | Toce_0853 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: tte:TTE1122 deacetylase; PFAM: histone deacetylase superfamily; SPTR: Deacetylases, including yeast histone deacetylase and acetoin utilization protein; PFAM: Histone deacetylase domain. | 0.947 |
| Toce_0324 | Toce_1146 | Toce_0324 | Toce_1146 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | Conserved hypothetical protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR006058; KEGG: tex:Teth514_1576 hypothetical protein; SPTR: Oxidoreductase FAD-binding domain protein. | 0.525 |
| Toce_0324 | Toce_1945 | Toce_0324 | Toce_1945 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | Helicase domain protein; InterPro IPR014001:IPR001650:IPR000330:IPR014021; KEGG: tex:Teth514_1830 helicase domain-containing protein; PFAM: helicase domain protein; SNF2-related protein; SMART: helicase domain protein; DEAD-like helicase; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain. | 0.930 |
| Toce_0324 | nagB | Toce_0324 | Toce_0326 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.581 |
| Toce_0325 | Toce_0324 | Toce_0325 | Toce_0324 | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | 0.566 |
| Toce_0325 | nagB | Toce_0325 | Toce_0326 | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.760 |