| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0264 | mtlD | Toce_0264 | Toce_0055 | Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR007737:IPR011608:IPR002178:IPR013011; KEGG: cdf:CD3083 transcription antiterminator; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Putative uncharacterized protein; PFAM: HTH domain; Mga helix-turn-helix domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. | D-mannitol 1-phosphate 5-dehydrogenase; COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118:IPR000669; KEGG: bbe:BBR47_56360 mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: Mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain. | 0.984 |
| Toce_0264 | nagB | Toce_0264 | Toce_0326 | Transcriptional antiterminator, BglG; COGs: COG3711 Transcriptional antiterminator; InterPro IPR007737:IPR011608:IPR002178:IPR013011; KEGG: cdf:CD3083 transcription antiterminator; PFAM: PRD domain protein; M trans-acting positive regulator; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Putative uncharacterized protein; PFAM: HTH domain; Mga helix-turn-helix domain; PRD domain; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.564 |
| Toce_0324 | Toce_0325 | Toce_0324 | Toce_0325 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | 0.566 |
| Toce_0324 | Toce_0327 | Toce_0324 | Toce_0327 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: tte:TTE0232 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. | 0.437 |
| Toce_0324 | nagB | Toce_0324 | Toce_0326 | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.581 |
| Toce_0325 | Toce_0324 | Toce_0325 | Toce_0324 | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | 0.566 |
| Toce_0325 | Toce_0327 | Toce_0325 | Toce_0327 | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: tte:TTE0232 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. | 0.798 |
| Toce_0325 | Toce_1997 | Toce_0325 | Toce_1997 | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation. Belongs to the peptidase M38 family. | 0.402 |
| Toce_0325 | nagB | Toce_0325 | Toce_0326 | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.760 |
| Toce_0327 | Toce_0324 | Toce_0327 | Toce_0324 | COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: tte:TTE0232 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. | COGs: COG1231 Monoamine oxidase; InterPro IPR002937; KEGG: cbe:Cbei_4105 amine oxidase; PFAM: amine oxidase; SPTR: Amine oxidase; PFAM: Flavin containing amine oxidoreductase. | 0.437 |
| Toce_0327 | Toce_0325 | Toce_0327 | Toce_0325 | COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: tte:TTE0232 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | 0.798 |
| Toce_0327 | glmM | Toce_0327 | Toce_1968 | COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: tte:TTE0232 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.653 |
| Toce_0327 | glmS | Toce_0327 | Toce_1967 | COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: tte:TTE0232 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.504 |
| Toce_0327 | nagB | Toce_0327 | Toce_0326 | COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: tte:TTE0232 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.999 |
| Toce_0846 | glmM | Toce_0846 | Toce_1968 | Bifunctional phosphoglucose/phosphomannose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR011857:IPR001347:IPR019490; KEGG: ate:Athe_0619 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS); PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase / glucose-6-phosphate isomerase; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/p [...] | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.696 |
| Toce_0846 | glmS | Toce_0846 | Toce_1967 | Bifunctional phosphoglucose/phosphomannose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR011857:IPR001347:IPR019490; KEGG: ate:Athe_0619 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS); PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase / glucose-6-phosphate isomerase; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/p [...] | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.932 |
| Toce_0846 | mtlD | Toce_0846 | Toce_0055 | Bifunctional phosphoglucose/phosphomannose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR011857:IPR001347:IPR019490; KEGG: ate:Athe_0619 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS); PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase / glucose-6-phosphate isomerase; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/p [...] | D-mannitol 1-phosphate 5-dehydrogenase; COGs: COG0246 Mannitol-1-phosphate/altronate dehydrogenase; InterPro IPR013131:IPR013118:IPR000669; KEGG: bbe:BBR47_56360 mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase domain; Mannitol dehydrogenase rossman domain; SPTR: Mannitol-1-phosphate 5-dehydrogenase; PFAM: Mannitol dehydrogenase C-terminal domain; Mannitol dehydrogenase Rossmann domain. | 0.931 |
| Toce_0846 | nagB | Toce_0846 | Toce_0326 | Bifunctional phosphoglucose/phosphomannose isomerase; COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR011857:IPR001347:IPR019490; KEGG: ate:Athe_0619 bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase-like; sugar isomerase (SIS); PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase / glucose-6-phosphate isomerase; TIGRFAM: bifunctional phosphoglucose/phosphomannose isomerase; PFAM: Bacterial phospho-glucose isomerase C-terminal region; SIS domain; TIGRFAM: bifunctional phosphoglucose/p [...] | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.942 |
| Toce_1997 | Toce_0325 | Toce_1997 | Toce_0325 | Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation. Belongs to the peptidase M38 family. | Transcriptional regulator, GntR family; COGs: COG2188 Transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gwc:GWCH70_2215 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain. | 0.402 |
| Toce_1997 | nagB | Toce_1997 | Toce_0326 | Isoaspartyl dipeptidase; Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation. Belongs to the peptidase M38 family. | Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.911 |