| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0327 | murQ | Toce_0327 | Toce_0344 | COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: tte:TTE0232 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.974 |
| Toce_0337 | Toce_0338 | Toce_0337 | Toce_0338 | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: amt:Amet_4188 phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit. | 0.572 |
| Toce_0337 | Toce_0339 | Toce_0337 | Toce_0339 | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. | 0.603 |
| Toce_0337 | Toce_0340 | Toce_0337 | Toce_0340 | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | COGs: COG1447 Phosphotransferase system cellobiose-specific component IIA; InterPro IPR003188; KEGG: sha:SH0190 hypothetical protein; PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; SPTR: Similar to phosphotransferase system; PFAM: PTS system, Lactose/Cellobiose specific IIA subunit. | 0.479 |
| Toce_0337 | Toce_0341 | Toce_0337 | Toce_0341 | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | YdjC family protein; COGs: COG3394 conserved hypothetical protein; InterPro IPR006879; KEGG: amt:Amet_4184 YdjC family protein; PFAM: YdjC family protein; SPTR: YdjC family protein; PFAM: YdjC-like protein. | 0.475 |
| Toce_0337 | Toce_0342 | Toce_0337 | Toce_0342 | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | ATPase BadF/BadG/BcrA/BcrD type; COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: tte:TTE0216 N-acetylglucosamine kinase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; SPTR: Predicted N-acetylglucosamine kinase; PFAM: BadF/BadG/BcrA/BcrD ATPase family. | 0.748 |
| Toce_0337 | Toce_0345 | Toce_0337 | Toce_0345 | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | 6-phospho-beta-glucosidase; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR019802:IPR001088; KEGG: tte:TTE0337 alpha-galactosidase/6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain. | 0.579 |
| Toce_0337 | Toce_0346 | Toce_0337 | Toce_0346 | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | Protein of unknown function UPF0157; COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: cbf:CLI_0936 hypothetical protein; PFAM: protein of unknown function UPF0157; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0157). | 0.411 |
| Toce_0337 | anmK | Toce_0337 | Toce_0343 | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.710 |
| Toce_0337 | murQ | Toce_0337 | Toce_0344 | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.799 |
| Toce_0338 | Toce_0337 | Toce_0338 | Toce_0337 | COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: amt:Amet_4188 phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit. | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | 0.572 |
| Toce_0338 | Toce_0339 | Toce_0338 | Toce_0339 | COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: amt:Amet_4188 phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit. | PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. | 0.996 |
| Toce_0338 | Toce_0340 | Toce_0338 | Toce_0340 | COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: amt:Amet_4188 phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit. | COGs: COG1447 Phosphotransferase system cellobiose-specific component IIA; InterPro IPR003188; KEGG: sha:SH0190 hypothetical protein; PFAM: phosphotransferase system PTS lactose/cellobiose-specific IIA subunit; SPTR: Similar to phosphotransferase system; PFAM: PTS system, Lactose/Cellobiose specific IIA subunit. | 0.998 |
| Toce_0338 | Toce_0341 | Toce_0338 | Toce_0341 | COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: amt:Amet_4188 phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit. | YdjC family protein; COGs: COG3394 conserved hypothetical protein; InterPro IPR006879; KEGG: amt:Amet_4184 YdjC family protein; PFAM: YdjC family protein; SPTR: YdjC family protein; PFAM: YdjC-like protein. | 0.770 |
| Toce_0338 | Toce_0342 | Toce_0338 | Toce_0342 | COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: amt:Amet_4188 phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit. | ATPase BadF/BadG/BcrA/BcrD type; COGs: COG2971 N-acetylglucosamine kinase; InterPro IPR002731; KEGG: tte:TTE0216 N-acetylglucosamine kinase; PFAM: ATPase BadF/BadG/BcrA/BcrD type; SPTR: Predicted N-acetylglucosamine kinase; PFAM: BadF/BadG/BcrA/BcrD ATPase family. | 0.665 |
| Toce_0338 | Toce_0345 | Toce_0338 | Toce_0345 | COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: amt:Amet_4188 phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit. | 6-phospho-beta-glucosidase; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR019802:IPR001088; KEGG: tte:TTE0337 alpha-galactosidase/6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain. | 0.970 |
| Toce_0338 | anmK | Toce_0338 | Toce_0343 | COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: amt:Amet_4188 phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.623 |
| Toce_0338 | murQ | Toce_0338 | Toce_0344 | COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: amt:Amet_4188 phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.586 |
| Toce_0339 | Toce_0337 | Toce_0339 | Toce_0337 | PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. | Transcriptional regulator, RpiR family; COGs: COG1737 Transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tex:Teth514_0168 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Transcriptional regulator, RpiR family; PFAM: Helix-turn-helix domain, rpiR family; SIS domain. | 0.603 |
| Toce_0339 | Toce_0338 | Toce_0339 | Toce_0338 | PTS system, lactose/cellobiose family IIC subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. | COGs: COG1440 Phosphotransferase system cellobiose-specific component IIB; InterPro IPR013012:IPR003501; KEGG: amt:Amet_4188 phosphotransferase system, lactose/cellobiose-specific IIB subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIB subunit; SPTR: PTS system; PFAM: PTS system, Lactose/Cellobiose specific IIB subunit. | 0.996 |