| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Toce_0345 | Toce_0346 | Toce_0345 | Toce_0346 | 6-phospho-beta-glucosidase; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR019802:IPR001088; KEGG: tte:TTE0337 alpha-galactosidase/6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain. | Protein of unknown function UPF0157; COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: cbf:CLI_0936 hypothetical protein; PFAM: protein of unknown function UPF0157; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0157). | 0.440 |
| Toce_0345 | anmK | Toce_0345 | Toce_0343 | 6-phospho-beta-glucosidase; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR019802:IPR001088; KEGG: tte:TTE0337 alpha-galactosidase/6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.757 |
| Toce_0345 | murQ | Toce_0345 | Toce_0344 | 6-phospho-beta-glucosidase; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR019802:IPR001088; KEGG: tte:TTE0337 alpha-galactosidase/6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.787 |
| Toce_0346 | Toce_0345 | Toce_0346 | Toce_0345 | Protein of unknown function UPF0157; COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: cbf:CLI_0936 hypothetical protein; PFAM: protein of unknown function UPF0157; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0157). | 6-phospho-beta-glucosidase; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR019802:IPR001088; KEGG: tte:TTE0337 alpha-galactosidase/6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain. | 0.440 |
| Toce_0346 | anmK | Toce_0346 | Toce_0343 | Protein of unknown function UPF0157; COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: cbf:CLI_0936 hypothetical protein; PFAM: protein of unknown function UPF0157; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0157). | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.405 |
| Toce_0346 | murQ | Toce_0346 | Toce_0344 | Protein of unknown function UPF0157; COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: cbf:CLI_0936 hypothetical protein; PFAM: protein of unknown function UPF0157; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0157). | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.440 |
| Toce_0346 | rnhB | Toce_0346 | Toce_1072 | Protein of unknown function UPF0157; COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: cbf:CLI_0936 hypothetical protein; PFAM: protein of unknown function UPF0157; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0157). | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.537 |
| anmK | Toce_0345 | Toce_0343 | Toce_0345 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 6-phospho-beta-glucosidase; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR019802:IPR001088; KEGG: tte:TTE0337 alpha-galactosidase/6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain. | 0.757 |
| anmK | Toce_0346 | Toce_0343 | Toce_0346 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Protein of unknown function UPF0157; COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: cbf:CLI_0936 hypothetical protein; PFAM: protein of unknown function UPF0157; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0157). | 0.405 |
| anmK | murQ | Toce_0343 | Toce_0344 | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.999 |
| murQ | Toce_0345 | Toce_0344 | Toce_0345 | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 6-phospho-beta-glucosidase; COGs: COG1486 Alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR019802:IPR001088; KEGG: tte:TTE0337 alpha-galactosidase/6-phospho-beta-glucosidase; PFAM: glycoside hydrolase family 4; SPTR: Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain. | 0.787 |
| murQ | Toce_0346 | Toce_0344 | Toce_0346 | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | Protein of unknown function UPF0157; COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: cbf:CLI_0936 hypothetical protein; PFAM: protein of unknown function UPF0157; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0157). | 0.440 |
| murQ | anmK | Toce_0344 | Toce_0343 | Glucokinase regulatory-like protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | Protein of unknown function UPF0075; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.999 |
| rnhB | Toce_0346 | Toce_1072 | Toce_0346 | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | Protein of unknown function UPF0157; COGs: COG2320 conserved hypothetical protein; InterPro IPR007344; KEGG: cbf:CLI_0936 hypothetical protein; PFAM: protein of unknown function UPF0157; SPTR: Putative uncharacterized protein; PFAM: Uncharacterised protein family (UPF0157). | 0.537 |